Development of bestatin-based activity-based probes for metallo-aminopeptidases

Por Harbut, Michael B., Velmourougane, Geetha, Reiss, Gilana, Chandramohanadas, Rajesh, Greenbaum, Doron C.
Publicado em 2008

Thioamide-Based Fluorescent Protease Sensors

Por Goldberg, Jacob M., Chen, Xing, Meinhardt, Nataline, Greenbaum, Doron C., Petersson, E. James
Publicado em 2014

OspC Is Potent Plasminogen Receptor on Surface of Borrelia burgdorferi

Por Önder, Özlem, Humphrey, Parris T., McOmber, Brian, Korobova, Farida, Francella, Nicholas, Greenbaum, Doron C., Brisson, Dustin
Publicado em 2012

The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion

Por Doyle, Patricia S., Zhou, Yuan M., Hsieh, Ivy, Greenbaum, Doron C., McKerrow, James H., Engel, Juan C.
Publicado em 2011

The Malaria Parasite Progressively Dismantles the Host Erythrocyte Cytoskeleton for Efficient Egress

Por Millholland, Melanie G., Chandramohanadas, Rajesh, Pizzarro, Angel, Wehr, Angela, Shi, Hui, Darling, Claire, Lim, Chwee Teck, Greenbaum, Doron C.
Publicado em 2011

Synthesis of new (-)-Bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase

Por Velmourougane, Geetha, Harbut, Michael B., Dalal, Seema, McGowan, Sheena, Oellig, Christine A., Meinhardt, Nataline, Whisstock, James C., Klemba, Michael, Greenbaum, Doron C.
Publicado em 2011

Development of α-Helical Calpain Probes by Mimicking a Natural Protein-Protein Interaction

Por Jo, Hyunil, Meinhardt, Nataline, Wu, Yibing, Kulkarni, Swapnil, Hu, Xiaozhen, Low, Kristin E., Davies, Peter L., DeGrado, William F., Greenbaum, Doron C.
Publicado em 2012

Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases

Por Harbut, Michael B., Velmourougane, Geetha, Dalal, Seema, Reiss, Gilana, Whisstock, James C., Onder, Ozlem, Brisson, Dustin, McGowan, Sheena, Klemba, Michael, Greenbaum, Doron C.
Publicado em 2011

Apicomplexan Parasites Co-Opt Host Calpains to Facilitate Their Escape from Infected Cells

Por Chandramohanadas, Rajesh, Davis, Paul H., Beiting, Daniel P., Harbut, Michael B., Darling, Claire, Velmourougane, Geetha, Lee, Ming Yeh, Greer, Peter A., Roos, David S., Greenbaum, Doron C.
Publicado em 2009

A Host GPCR Signaling Network Required for the Cytolysis of Infected Cells Facilitates Release of Apicomplexan Parasites

Por Millholland, Melanie G., Mishra, Satish, Dupont, Christopher D., Love, Melissa S., Patel, Bhumit, Shilling, Dustin, Kazanietz, Marcelo G., Foskett, J. Kevin, Hunter, Christopher A., Sinnis, Photini, Greenbaum, Doron C.
Publicado em 2013

A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells

Por Shah, Parag P., Wang, Tianhua, Kaletsky, Rachel L., Myers, Michael C., Purvis, Jeremy E., Jing, Huiyan, Huryn, Donna M., Greenbaum, Doron C., Smith, Amos B., Bates, Paul, Diamond, Scott L.
Publicado em 2010

Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design

Por Harbut, Michael B., Patel, Bhumit A., Yeung, Bryan K. S., McNamara, Case W., Bright, A. Taylor, Ballard, Jaime, Supek, Frantisek, Golde, Todd E., Winzeler, Elizabeth A., Diagana, Thierry T., Greenbaum, Doron C.
Publicado em 2012

Discovery of Potent Small-Molecule Inhibitors of Multidrug-Resistant Plasmodium falciparum Using a Novel Miniaturized High-Throughput Luciferase-Based Assay

Por Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D., Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison E., Jing, Huiyan, Ward, Stephen A., Biagini, Giancarlo A., DeGrado, William F., Diamond, Scott L., Greenbaum, Doron C.
Publicado em 2010

Platelet Factor 4 Activity against P. falciparum and Its Translation to Nonpeptidic Mimics as Antimalarials

Por Love, Melissa S., Millholland, Melanie G., Mishra, Satish, Kulkarni, Swapnil, Freeman, Katie B., Pan, Wenxi, Kavash, Robert W., Costanzo, Michael J., Jo, Hyunil, Daly, Thomas M., Williams, Dewight R., Kowalska, M. Anna, Bergman, Lawrence W., Poncz, Mortimer, DeGrado, William F., Sinnis, Photini, Scott, Richard W., Greenbaum, Doron C.
Publicado em 2012