Thioamide-Based Fluorescent Protease Sensors

[Image: see text] Thioamide quenchers can be paired with compact fluorophores to design “turn-on” fluorescent protease substrates. We have used this method to study a variety of serine-, cysteine-, carboxyl-, and metallo-proteases, including trypsin, chymotrypsin, pepsin, thermolysin, papain, and ca...

Full description

Saved in:
Bibliographic Details
Main Authors: Goldberg, Jacob M., Chen, Xing, Meinhardt, Nataline, Greenbaum, Doron C., Petersson, E. James
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985465/
https://ncbi.nlm.nih.gov/pubmed/24472041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412297x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items