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Minimalist Probes for Studying Protein Dynamics: Thioamide Quenching of Selectively Excitable Fluorescent Amino Acids

Fluorescent probe pairs that can be selectively excited in the presence of Trp and Tyr are of great utility in studying conformational changes in proteins. However, the size of these probe pairs can restrict their incorporation to small portions of a protein sequence where their effects on secondary...

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Main Authors: Goldberg, Jacob M., Speight, Lee C., Fegley, Mark W., Petersson, E. James
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360930/
https://ncbi.nlm.nih.gov/pubmed/22471784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3005094
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