Emerging treatment options for cryptosporidiosis

par Love, Melissa S., Choy, Robert K.M.
Publié dans Curr Opin Infect Dis (2021)

A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis

par Love, Melissa S., Beasley, Federico C., Jumani, Rajiv S., Wright, Timothy M., Chatterjee, Arnab K., Huston, Christopher D., Schultz, Peter G., McNamara, Case W.
Publié dans PLoS Negl Trop Dis (2017)

Solution structure of CCL21 and identification of a putative CCR7 binding site

par Love, Melissa, Sandberg, Jamie L., Ziarek, Joshua J., Gerarden, Kyle P., Rode, Renee R., Jensen, Davin R., McCaslin, Darrell R., Peterson, Francis C., Veldkamp, Christopher T.
Publié 2012

A Host GPCR Signaling Network Required for the Cytolysis of Infected Cells Facilitates Release of Apicomplexan Parasites

par Millholland, Melanie G., Mishra, Satish, Dupont, Christopher D., Love, Melissa S., Patel, Bhumit, Shilling, Dustin, Kazanietz, Marcelo G., Foskett, J. Kevin, Hunter, Christopher A., Sinnis, Photini, Greenbaum, Doron C.
Publié 2013

A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors

par Jumani, Rajiv S., Hasan, Muhammad M., Stebbins, Erin E., Donnelly, Liam, Miller, Peter, Klopfer, Connor, Bessoff, Kovi, Teixeira, Jose E., Love, Melissa S., McNamara, Case W., Huston, Christopher D.
Publié dans Nat Commun (2019)

Molecular Testing for Mycoplasma genitalium in the United States: Results from the AMES Prospective Multicenter Clinical Study

par Gaydos, Charlotte A., Manhart, Lisa E., Taylor, Stephanie N., Lillis, Rebecca A., Hook, Edward W., Klausner, Jeffrey D., Remillard, Carmelle V., Love, Melissa, McKinney, Byron, Getman, Damon K.
Publié dans J Clin Microbiol (2019)

Characteristics of Mycoplasma genitalium Urogenital Infections in a Diverse Patient Sample from the United States: Results from the Aptima Mycoplasma genitalium Evaluation Study (A...

par Manhart, Lisa E., Gaydos, Charlotte A., Taylor, Stephanie N., Lillis, Rebecca A., Hook, Edward W., Klausner, Jeffrey D., Remillard, Carmelle V., Love, Melissa, McKinney, Byron, Getman, Damon K.
Publié dans J Clin Microbiol (2020)

Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis

par Lunde, Christopher S., Stebbins, Erin E., Jumani, Rajiv S., Hasan, Md Mahmudul, Miller, Peter, Barlow, John, Freund, Yvonne R., Berry, Pamela, Stefanakis, Rianna, Gut, Jiri, Rosenthal, Philip J., Love, Melissa S., McNamara, Case W., Easom, Eric, Plattner, Jacob J., Jacobs, Robert T., Huston, Christopher D.
Publié dans Nat Commun (2019)

Platelet Factor 4 Activity against P. falciparum and Its Translation to Nonpeptidic Mimics as Antimalarials

par Love, Melissa S., Millholland, Melanie G., Mishra, Satish, Kulkarni, Swapnil, Freeman, Katie B., Pan, Wenxi, Kavash, Robert W., Costanzo, Michael J., Jo, Hyunil, Daly, Thomas M., Williams, Dewight R., Kowalska, M. Anna, Bergman, Lawrence W., Poncz, Mortimer, DeGrado, William F., Sinnis, Photini, Scott, Richard W., Greenbaum, Doron C.
Publié 2012

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

par Janes, Jeff, Young, Megan E., Chen, Emily, Rogers, Nicole H., Burgstaller-Muehlbacher, Sebastian, Hughes, Laura D., Love, Melissa S., Hull, Mitchell V., Kuhen, Kelli L., Woods, Ashley K., Joseph, Sean B., Petrassi, H. Michael, McNamara, Case W., Tremblay, Matthew S., Su, Andrew I., Schultz, Peter G., Chatterjee, Arnab K.
Publié dans Proc Natl Acad Sci U S A (2018)

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis

par Hulverson, Matthew A., Choi, Ryan, Arnold, Samuel L.M., Schaefer, Deborah A., Hemphill, Andrew, McCloskey, Molly C., Betzer, Dana P., Müller, Joachim, Vidadala, Rama S.R., Whitman, Grant R., Rivas, Kasey L., Barrett, Lynn K., Hackman, Robert C., Love, Melissa S., McNamara, Case W., Shaughnessy, Thomas K., Kondratiuk, Alison, Kurnick, Matthew, Banfor, Patricia N., Lynch, James J., Freiberg, Gail M., Kempf, Dale J., Maly, Dustin J., Riggs, Michael W., Ojo, Kayode K., Van Voorhis, Wesley C.
Publié dans Int J Parasitol (2017)

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

par Baragaña, Beatriz, Forte, Barbara, Choi, Ryan, Nakazawa Hewitt, Stephen, Bueren-Calabuig, Juan A., Pisco, João Pedro, Peet, Caroline, Dranow, David M., Robinson, David A., Jansen, Chimed, Norcross, Neil R., Vinayak, Sumiti, Anderson, Mark, Brooks, Carrie F., Cooper, Caitlin A., Damerow, Sebastian, Delves, Michael, Dowers, Karen, Duffy, James, Edwards, Thomas E., Hallyburton, Irene, Horst, Benjamin G., Hulverson, Matthew A., Ferguson, Liam, Jiménez-Díaz, María Belén, Jumani, Rajiv S., Lorimer, Donald D., Love, Melissa S., Maher, Steven, Matthews, Holly, McNamara, Case W., Miller, Peter, O’Neill, Sandra, Ojo, Kayode K., Osuna-Cabello, Maria, Pinto, Erika, Post, John, Riley, Jennifer, Rottmann, Matthias, Sanz, Laura M., Scullion, Paul, Sharma, Arvind, Shepherd, Sharon M., Shishikura, Yoko, Simeons, Frederick R. C., Stebbins, Erin E., Stojanovski, Laste, Straschil, Ursula, Tamaki, Fabio K., Tamjar, Jevgenia, Torrie, Leah S., Vantaux, Amélie, Witkowski, Benoît, Wittlin, Sergio, Yogavel, Manickam, Zuccotto, Fabio, Angulo-Barturen, Iñigo, Sinden, Robert, Baum, Jake, Gamo, Francisco-Javier, Mäser, Pascal, Kyle, Dennis E., Winzeler, Elizabeth A., Myler, Peter J., Wyatt, Paul G., Floyd, David, Matthews, David, Sharma, Amit, Striepen, Boris, Huston, Christopher D., Gray, David W., Fairlamb, Alan H., Pisliakov, Andrei V., Walpole, Chris, Read, Kevin D., Van Voorhis, Wesley C., Gilbert, Ian H.
Publié dans Proc Natl Acad Sci U S A (2019)