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Solution structure of CCL21 and identification of a putative CCR7 binding site
CCL21 is a human chemokine that recruits normal immune cells and metastasizing tumor cells to lymph nodes through activation of the G protein-coupled receptor CCR7. The CCL21 structure solved by NMR contains a conserved chemokine domain followed by an extended, unstructured C-terminus that is not ty...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3272885/ https://ncbi.nlm.nih.gov/pubmed/22221265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201601k |
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