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Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening
RAD51 is a key protein of homologous recombination that plays a critical role in the repair of DNA double-strand breaks (DSB) and interstrand cross links (ICL). To better understand the cellular function(s) of human RAD51, we propose to develop specific RAD51 inhibitors. RAD51 inhibitors may also he...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117970/ https://ncbi.nlm.nih.gov/pubmed/21428443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100428c |
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