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Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening
BACKGROUND: Duchenne muscular dystrophy (DMD) is a devastating muscle wasting disease caused by mutations in dystrophin, a muscle cytoskeletal protein. Utrophin is a homologue of dystrophin that can functionally compensate for its absence when expressed at increased levels in the myofibre, as shown...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3197614/ https://ncbi.nlm.nih.gov/pubmed/22028826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026169 |
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