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The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a lethal neuromuscular disorder caused by loss of dystrophin. Several therapeutic modalities are currently in clinical trials but none will achieve maximum functional rescue and full disease correction. Therefore, we explored the potential of combining the benefi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: Guiraud, Simon, Edwards, Benjamin, Babbs, Arran, Squire, Sarah E, Berg, Adam, Moir, Lee, Wood, Matthew J, Davies, Kay E
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586144/
https://ncbi.nlm.nih.gov/pubmed/30990876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz049
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