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Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin‐deficient mice and Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a fatal disorder caused by absence of functional dystrophin protein. Compensation in dystrophin‐deficient (mdx) mice may be achieved by overexpression of its fetal paralogue, utrophin. Strategies to increase utrophin levels by stimulating promoter activity using...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Lett
Egile Nagusiak: Perkins, Kelly J., Davies, Kay E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032923/
https://ncbi.nlm.nih.gov/pubmed/29772070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13099
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