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A Sensitive Luminescent Assay for the Histone Methyltransferase NSD1 and Other SAM-Dependent Enzymes

A major focus of our pediatric cancer research is the discovery of chemical probes to further our understanding of the biology of leukemia harboring fusion proteins arising from chromosomal rearrangements, and to develop novel specifically targeted therapies. The NUP98-NSD1 fusion protein occurs in...

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Detalhes bibliográficos
Main Authors: Drake, Katherine M., Watson, Venita G., Kisielewski, Anne, Glynn, Rebecca, Napper, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060815/
https://ncbi.nlm.nih.gov/pubmed/24927133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2014.583
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