Induction of Ectopic Olfactory Structures and Bone Morphogenetic Protein Inhibition by Rossy, a Group XII Secreted Phospholipase A(2)

Por Muñoz-Sanjuán, Ignacio, Brivanlou, Ali H.
Publicado em 2005

The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease

Por Munoz-Sanjuan, Ignacio, Bates, Gillian P.
Publicado em 2011

Unravelling and exploiting astrocyte dysfunction in Huntington's disease

Por Khakh, Baljit S., Beaumont, Vahri, Cachope, Roger, Munoz-Sanjuan, Ignacio, Goldman, Steven A., Grantyn, Rosemarie
Publicado no Trends Neurosci (2017)

Pharmacokinetics of memantine in rats and mice

Por Beconi, Maria G., Howland, David, Park, Larry, Lyons, Kathryn, Giuliano, Joseph, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Pacifici, Robert
Publicado em 2012

Efficacy of Selective PDE4D Negative Allosteric Modulators in the Object Retrieval Task in Female Cynomolgus Monkeys (Macaca fascicularis)

Por Sutcliffe, Jane S., Beaumont, Vahri, Watson, James M., Chew, Chang Sing, Beconi, Maria, Hutcheson, Daniel M., Dominguez, Celia, Munoz-Sanjuan, Ignacio
Publicado em 2014

Quantifying autophagy using novel LC3B and p62 TR-FRET assays

Por Bresciani, Alberto, Spiezia, Maria Carolina, Boggio, Roberto, Cariulo, Cristina, Nordheim, Anja, Altobelli, Roberta, Kuhlbrodt, Kirsten, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Wityak, John, Fodale, Valentina, Marchionini, Deanna M., Weiss, Andreas
Publicado no PLoS One (2018)

Characterization of HTT Inclusion Size, Location, and Timing in the zQ175 Mouse Model of Huntington´s Disease: An In Vivo High-Content Imaging Study

Por Carty, Nikisha, Berson, Nadège, Tillack, Karsten, Thiede, Christina, Scholz, Diana, Kottig, Karsten, Sedaghat, Yalda, Gabrysiak, Christina, Yohrling, George, von der Kammer, Heinz, Ebneth, Andreas, Mack, Volker, Munoz-Sanjuan, Ignacio, Kwak, Seung
Publicado no PLoS One (2015)

The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington’s Disease

Por Beaumont, Vahri, Park, Larry, Rassoulpour, Arash, Dijkman, Ulrike, Heikkinen, Taneli, Lehtimaki, Kimmo, Kontkanen, Outi, Al Nackkash, Rand, Bates, Gillian P., Gleyzes, Melanie, Steidl, Esther, Ramboz, Sylvie, Murphy, Carol, Beconi, Maria G., Dominguez, Celia, Munoz-Sanjuan, Ignacio
Publicado em 2014

Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin

Por Ko, Jan, Isas, J Mario, Sabbaugh, Adam, Yoo, Jung Hyun, Pandey, Nitin K, Chongtham, Anjalika, Ladinsky, Mark, Wu, Wei-Li, Rohweder, Heike, Weiss, Andreas, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Langen, Ralf, Patterson, Paul H, Khoshnan, Ali
Publicado no Hum Mol Genet (2018)

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

Por Heikkinen, Taneli, Lehtimäki, Kimmo, Vartiainen, Nina, Puoliväli, Jukka, Hendricks, Susan J., Glaser, Jack R., Bradaia, Amyaouch, Wadel, Kristian, Touller, Chrystelle, Kontkanen, Outi, Yrjänheikki, Juha M., Buisson, Bruno, Howland, David, Beaumont, Vahri, Munoz-Sanjuan, Ignacio, Park, Larry C.
Publicado em 2012

Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins

Por Macdonald, Douglas, Tessari, Michela A., Boogaard, Ivette, Smith, Melanie, Pulli, Kristiina, Szynol, Agnieszka, Albertus, Faywell, Lamers, Marieke B. A. C., Dijkstra, Sipke, Kordt, Daniel, Reindl, Wolfgang, Herrmann, Frank, McAllister, George, Fischer, David F., Munoz-Sanjuan, Ignacio
Publicado em 2014

SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's Disease

Por Wityak, John, Prime, Michael E., Brookfield, Frederick A., Courtney, Stephen M., Erfan, Sayeh, Johnsen, Siw, Johnson, Peter D., Li, Marie, Marston, Richard W., Reed, Laura, Vaidya, Darshan, Schaertl, Sabine, Pedret-Dunn, Anna, Beconi, Maria, Macdonald, Douglas, Muñoz-Sanjuan, Ignacio, Dominguez, Celia
Publicado em 2012

A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease

Por Todd, Daniel, Gowers, Ian, Dowler, Simon J., Wall, Michael D., McAllister, George, Fischer, David F., Dijkstra, Sipke, Fratantoni, Silvina A., van de Bospoort, Rhea, Veenman-Koepke, Jessica, Flynn, Geraldine, Arjomand, Jamshid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Wityak, John, Bard, Jonathan A.
Publicado em 2014

Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease

Por Prime, Michael E., Brookfield, Frederick A., Courtney, Stephen M., Gaines, Simon, Marston, Richard W., Ichihara, Osamu, Li, Marie, Vaidya, Darshan, Williams, Helen, Pedret-Dunn, Anna, Reed, Laura, Schaertl, Sabine, Toledo-Sherman, Leticia, Beconi, Maria, Macdonald, Douglas, Muñoz-Sanjuan, Ignacio, Dominguez, Celia, Wityak, John
Publicado em 2012

Oral Administration of the Pimelic Diphenylamide HDAC Inhibitor HDACi 4b Is Unsuitable for Chronic Inhibition of HDAC Activity in the CNS In Vivo

Por Beconi, Maria, Aziz, Omar, Matthews, Kim, Moumné, Lara, O’Connell, Catherine, Yates, Dawn, Clifton, Steven, Pett, Hannah, Vann, Julie, Crowley, Lynsey, Haughan, Alan F., Smith, Donna L., Woodman, Ben, Bates, Gillian P., Brookfield, Fred, Bürli, Roland W., McAllister, George, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Beaumont, Vahri
Publicado em 2012

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

Por Benraiss, Abdellatif, Wang, Su, Herrlinger, Stephanie, Li, Xiaojie, Chandler-Militello, Devin, Mauceri, Joseph, Burm, Hayley B., Toner, Michael, Osipovitch, Mikhail, Jim Xu, Qiwu, Ding, Fengfei, Wang, Fushun, Kang, Ning, Kang, Jian, Curtin, Paul C., Brunner, Daniela, Windrem, Martha S., Munoz-Sanjuan, Ignacio, Nedergaard, Maiken, Goldman, Steven A.
Publicado no Nat Commun (2016)

Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease

Por Menalled, Liliana B., Kudwa, Andrea E., Oakeshott, Steve, Farrar, Andrew, Paterson, Neil, Filippov, Igor, Miller, Sam, Kwan, Mei, Olsen, Michael, Beltran, Jose, Torello, Justin, Fitzpatrick, Jon, Mushlin, Richard, Cox, Kimberly, McConnell, Kristi, Mazzella, Matthew, He, Dansha, Osborne, Georgina F., Al-Nackkash, Rand, Bates, Gill P., Tuunanen, Pasi, Lehtimaki, Kimmo, Brunner, Dani, Ghavami, Afshin, Ramboz, Sylvie, Park, Larry, Macdonald, Douglas, Munoz-Sanjuan, Ignacio, Howland, David
Publicado em 2014

Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington’s disease mice

Por Bondulich, Marie K., Jolinon, Nelly, Osborne, Georgina F., Smith, Edward J., Rattray, Ivan, Neueder, Andreas, Sathasivam, Kirupa, Ahmed, Mhoriam, Ali, Nadira, Benjamin, Agnesska C., Chang, Xiaoli, Dick, James R. T., Ellis, Matthew, Franklin, Sophie A., Goodwin, Daniel, Inuabasi, Linda, Lazell, Hayley, Lehar, Adam, Richard-Londt, Angela, Rosinski, Jim, Smith, Donna L., Wood, Tobias, Tabrizi, Sarah J., Brandner, Sebastian, Greensmith, Linda, Howland, David, Munoz-Sanjuan, Ignacio, Lee, Se-Jin, Bates, Gillian P.
Publicado no Sci Rep (2017)