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The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease
Huntington disease (HD) is a dominantly inherited neurodegenerative disorder that results from expansion of the polyglutamine repeat in the huntingtin (HTT) gene. There are currently no effective treatments for this devastating disease. Given its monogenic nature, disease modification therapies for...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026740/ https://ncbi.nlm.nih.gov/pubmed/21285520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45364 |
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