More Modifiers Move on DNA Damage

Por Morris, Joanna R
Publicado em 2010

Attenuation of the ubiquitin conjugate DNA damage signal by the proteasomal DUB POH1

Por Morris, Joanna R.
Publicado em 2012

The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair

Por Densham, Ruth M., Morris, Joanna R.
Publicado no Nucleus (2016)

SUMO, a small, but powerful, regulator of double-strand break repair

Por Garvin, Alexander J., Morris, Joanna R.
Publicado no Philos Trans R Soc Lond B Biol Sci (2017)

Moving Mountains—The BRCA1 Promotion of DNA Resection

Por Densham, Ruth M., Morris, Joanna R.
Publicado no Front Mol Biosci (2019)

BRCA1-BARD1: the importance of being in shape

Por Daza-Martin, Manuel, Densham, Ruth M., Morris, Joanna R.
Publicado no Mol Cell Oncol (2019)

USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A

Por Uckelmann, Michael, Densham, Ruth M., Baas, Roy, Winterwerp, Herrie H. K., Fish, Alexander, Sixma, Titia K., Morris, Joanna R.
Publicado no Nat Commun (2018)

GSK3β-SCF(FBXW7α) mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover

Por Garvin, Alexander J, Khalaf, Ahmed H A, Rettino, Alessandro, Xicluna, Jerome, Butler, Laura, Morris, Joanna R, Heery, David M, Clarke, Nicole M
Publicado no Nucleic Acids Res (2019)

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair

Por Garvin, Alexander J, Densham, Ruth M, Blair-Reid, Sarah A, Pratt, Kenny M, Stone, Helen R, Weekes, Daniel, Lawrence, Kirsty J, Morris, Joanna R
Publicado em 2013

DNA methylation profiling to assess pathogenicity of BRCA1 unclassified variants in breast cancer

Por Flower, Kirsty J, Shenker, Natalie S, El-Bahrawy, Mona, Goldgar, David E, Parsons, Michael T, Spurdle, Amanda B, Morris, Joanna R, Brown, Robert, Flanagan, James M
Publicado no Epigenetics (2016)

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

Por Butler, Laura R, Densham, Ruth M, Jia, Junying, Garvin, Alexander J, Stone, Helen R, Shah, Vandna, Weekes, Daniel, Festy, Frederic, Beesley, James, Morris, Joanna R
Publicado em 2012

Discovery of peptide ligands targeting a specific ubiquitin-like domain–binding site in the deubiquitinase USP11

Por Spiliotopoulos, Anastasios, Blokpoel Ferreras, Lia, Densham, Ruth M., Caulton, Simon G., Maddison, Ben C., Morris, Joanna R., Dixon, James E., Gough, Kevin C., Dreveny, Ingrid
Publicado no J Biol Chem (2019)

PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts

Por Piberger, Ann Liza, Bowry, Akhil, Kelly, Richard D. W., Walker, Alexandra K., González-Acosta, Daniel, Bailey, Laura J., Doherty, Aidan J., Méndez, Juan, Morris, Joanna R., Bryant, Helen E., Petermann, Eva
Publicado no Nat Commun (2020)

The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms

Por Garvin, Alexander J., Walker, Alexandra K., Densham, Ruth M., Chauhan, Anoop Singh, Stone, Helen R., Mackay, Hannah L., Jamshad, Mohammed, Starowicz, Katarzyna, Daza-Martin, Manuel, Ronson, George E., Lanz, Alexander J., Beesley, James F., Morris, Joanna R.
Publicado no Genes Dev (2019)

The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment

Por Monteiro, Lara J., Khongkow, Pasarat, Kongsema, Mesayamas, Morris, Joanna R., Man, Cornelia, Weekes, Daniel, Koo, Chuay-Yeng, Gomes, Ana R., Pinto, Paola H., Varghese, Vidhya, Kenny, Laura M., Coombes, R. Charles, Freire, Raimundo, Medema, René H., Lam, Eric W.-F.
Publicado em 2012

Human BRCA1-BARD1 Ubiquitin ligase activity counters chromatin barriers to DNA resection

Por Densham, Ruth M, Garvin, Alexander J., Stone, Helen R., Strachan, Joanna, Baldock, Robert A, Daza-Martin, Manuel, Fletcher, Alice, Blair-Reid, Sarah, Beesley, James, Johal, Balraj, Pearl, Laurence H., Neely, Robert, Keep, Nicholas H., Watts, Felicity Z, Morris, Joanna R.
Publicado no Nat Struct Mol Biol (2016)

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Por Eccles, Suzanne A, Aboagye, Eric O, Ali, Simak, Anderson, Annie S, Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P, Brennan, Keith, Brown, Nicola J, Bryant, Helen E, Bundred, Nigel J, Burchell, Joy M, Campbell, Anna M, Carroll, Jason S, Clarke, Robert B, Coles, Charlotte E, Cook, Gary JR, Cox, Angela, Curtin, Nicola J, Dekker, Lodewijk V, dos Santos Silva, Isabel, Duffy, Stephen W, Easton, Douglas F, Eccles, Diana M, Edwards, Dylan R, Edwards, Joanne, Evans, D Gareth, Fenlon, Deborah F, Flanagan, James M, Foster, Claire, Gallagher, William M, Garcia-Closas, Montserrat, Gee, Julia M W, Gescher, Andy J, Goh, Vicky, Groves, Ashley M, Harvey, Amanda J, Harvie, Michelle, Hennessy, Bryan T, Hiscox, Stephen, Holen, Ingunn, Howell, Sacha J, Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S, Jasani, Bharat, Jones, Louise J, Key, Timothy J, Kirwan, Cliona C, Kong, Anthony, Kunkler, Ian H, Langdon, Simon P, Leach, Martin O, Mann, David J, Marshall, John F, Martin, Lesley Ann, Martin, Stewart G, Macdougall, Jennifer E, Miles, David W, Miller, William R, Morris, Joanna R, Moss, Sue M, Mullan, Paul, Natrajan, Rachel, O’Connor, James PB, O’Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D P, Rakha, Emad A, Reed, Elizabeth, Robinson, Simon P, Sahai, Erik, Saxton, John M, Schmid, Peter, Smalley, Matthew J, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H, Tutt, Andrew N J, Velikova, Galina, Walker, Rosemary A, Watson, Christine J, Williams, Kaye J, Young, Leonie S, Thompson, Alastair M
Publicado em 2013