Matrix metalloproteinases: protective roles in cancer

Por Decock, Julie, Thirkettle, Sally, Wagstaff, Laura, Edwards, Dylan R
Publicado no J Cell Mol Med (2011)

The ADAMTS metalloproteinases

Por Porter, Sarah, Clark, Ian M., Kevorkian, Lara, Edwards, Dylan R.
Publicado em 2005

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

Por Kelwick, Richard, Desanlis, Ines, Wheeler, Grant N, Edwards, Dylan R
Publicado no Genome Biol (2015)

G-helix of Maspin Mediates Effects on Cell Migration and Adhesion

Por Ravenhill, Lorna, Wagstaff, Laura, Edwards, Dylan R., Ellis, Vincent, Bass, Rosemary
Publicado em 2010

Genome-Wide Responses of Female Fruit Flies Subjected to Divergent Mating Regimes

Por Gerrard, Dave T., Fricke, Claudia, Edward, Dominic A., Edwards, Dylan R., Chapman, Tracey
Publicado em 2013

ADAM and ADAMTS gene expression in native and wound healing human lens epithelial cells

Por Hodgkinson, Lisa M., Wang, Lixin, Duncan, George, Edwards, Dylan R., Wormstone, I. Michael
Publicado em 2010

TGF-β-Elicited Induction of Tissue Inhibitor of Metalloproteinases (TIMP)-3 Expression in Fibroblasts Involves Complex Interplay between Smad3, p38α, and ERK1/2

Por Leivonen, Suvi-Katri, Lazaridis, Konstantinos, Decock, Julie, Chantry, Andrew, Edwards, Dylan R., Kähäri, Veli-Matti
Publicado em 2013

Matrix Metalloproteinase 8 (Collagenase 2) Induces the Expression of Interleukins 6 and 8 in Breast Cancer Cells

Por Thirkettle, Sally, Decock, Julie, Arnold, Hugh, Pennington, Caroline J., Jaworski, Diane M., Edwards, Dylan R.
Publicado em 2013

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Por Decock, Julie, Hendrickx, Wouter, Thirkettle, Sally, Gutiérrez-Fernández, Ana, Robinson, Stephen D, Edwards, Dylan R
Publicado no Breast Cancer Res (2015)

Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets

Por Radomski, Anna, Jurasz, Paul, Sanders, Esmond J, Overall, Christopher M, Bigg, Heather F, Edwards, Dylan R, Radomski, Marek W
Publicado em 2002

Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).

Por Worley, Joanna R, Thompkins, Philip B, Lee, Meng H, Hutton, Mike, Soloway, Paul, Edwards, Dylan R, Murphy, Gillian, Knäuper, Vera
Publicado em 2003

Brk Protects Breast Cancer Cells from Autophagic Cell Death Induced by Loss of Anchorage

Por Harvey, Amanda J., Pennington, Caroline J., Porter, Sarah, Burmi, Rajpal S., Edwards, Dylan R., Court, William, Eccles, Suzanne A., Crompton, Mark R.
Publicado em 2009

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

Por Young, David A, Lakey, Rachel L, Pennington, Caroline J, Jones, Debra, Kevorkian, Lara, Edwards, Dylan R, Cawston, Timothy E, Clark, Ian M
Publicado em 2005

Altered Balance Between Matrix Metalloproteinases and Their Inhibitors in Experimental Biliary Fibrosis

Por Kossakowska, Anna E., Edwards, Dylan R., Lee, Samuel S., Urbanski, Lawrence S., Stabbler, Andrea L., Zhang, Chun-Li, Phillips, Blaine W., Zhang, Yikun, Urbanski, Stefan J.
Publicado em 1998

Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene.

Por Young, David A, Phillips, Blaine W, Lundy, Caroline, Nuttall, Robert K, Hogan, Aileen, Schultz, Gilbert A, Leco, Kevin J, Clark, Ian M, Edwards, Dylan R
Publicado em 2002

Matrix Metalloproteinase 13 Is Induced in Fibroblasts in Polyomavirus Middle T Antigen-Driven Mammary Carcinoma without Influencing Tumor Progression

Por Nielsen, Boye S., Egeblad, Mikala, Rank, Fritz, Askautrud, Hanne A., Pennington, Caroline J., Pedersen, Tanja X., Christensen, Ib J., Edwards, Dylan R., Werb, Zena, Lund, Leif R.
Publicado em 2008

Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function

Por Sarper, Muge, Allen, Michael D., Gomm, Jenny, Haywood, Linda, Decock, Julie, Thirkettle, Sally, Ustaoglu, Ahsen, Sarker, Shah-Jalal, Marshall, John, Edwards, Dylan R., Jones, J. Louise
Publicado no Breast Cancer Res (2017)

Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms

Por Hancox, Rachael A, Allen, Michael D, Holliday, Deborah L, Edwards, Dylan R, Pennington, Caroline J, Guttery, David S, Shaw, Jacqueline A, Walker, Rosemary A, Pringle, J Howard, Jones, J Louise
Publicado em 2009

Development of a novel tumor-targeted vascular disrupting agent activated by MT-MMPs

Por Atkinson, Jennifer M, Falconer, Robert A, Edwards, Dylan R, Pennington, Caroline J, Siller, Catherine S, Shnyder, Steven D, Bibby, Michael C, Patterson, Laurence H, Loadman, Paul M, Gill, Jason H
Publicado em 2010

Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis

Por Ellison, Tim S., Atkinson, Samuel J., Steri, Veronica, Kirkup, Benjamin M., Preedy, Michael E. J., Johnson, Robert T., Ruhrberg, Christiana, Edwards, Dylan R., Schneider, Jochen G., Weilbaecher, Katherine, Robinson, Stephen D.
Publicado no Dis Model Mech (2015)