Inactivation of apaziquone by haematuria: implications for the design of phase III clinical trials against non-muscle invasive bladder cancer

Por Phillips, Roger M., Loadman, Paul M., Reddy, Guru
Publicado no Cancer Chemother Pharmacol (2019)

Effect of Eicosapentaenoic Acid on E-type Prostaglandin Synthesis and EP4 Receptor Signaling in Human Colorectal Cancer Cells

Por Hawcroft, Gillian, Loadman, Paul M, Belluzzi, Andrea, Hull, Mark A
Publicado em 2010

FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms

Por Tomlinson, Darren C., Baxter, Euan W., Loadman, Paul M., Hull, Mark A., Knowles, Margaret A.
Publicado em 2012

Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment

Por Elkashef, Sara M., Allison, Simon J., Sadiq, Maria, Basheer, Haneen A., Ribeiro Morais, Goreti, Loadman, Paul M., Pors, Klaus, Falconer, Robert A.
Publicado no Sci Rep (2016)

A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme...

Por Hull, Mark A, Sandell, Anna C, Montgomery, Alan A, Logan, Richard FA, Clifford, Gayle M, Rees, Colin J, Loadman, Paul M, Whitham, Diane
Publicado em 2013

MMP-10 Is Overexpressed, Proteolytically Active, and a Potential Target for Therapeutic Intervention in Human Lung Carcinomas

Por Gill, Jason H, Kirwan, Ian G, Seargent, Jill M, Martin, Sandie W, Tijani, Sidiq, Anikin, Vladimir A, Mearns, Alan J, Bibby, Michael C, Anthoney, Alan, Loadman, Paul M
Publicado em 2004

Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

Por Volpato, Milene, Ingram, Nicola, Perry, Sarah L, Spencer, Jade, Race, Amanda D, Marshall, Catriona, Hutchinson, John M, Nicolaou, Anna, Loadman, Paul M, Coletta, P Louise, Hull, Mark A
Publicado no Cancer Chemother Pharmacol (2020)

Development of a novel tumor-targeted vascular disrupting agent activated by MT-MMPs

Por Atkinson, Jennifer M, Falconer, Robert A, Edwards, Dylan R, Pennington, Caroline J, Siller, Catherine S, Shnyder, Steven D, Bibby, Michael C, Patterson, Laurence H, Loadman, Paul M, Gill, Jason H
Publicado em 2010

Eicosapentaenoic acid and aspirin, alone and in combination, for the prevention of colorectal adenomas (seAFOod Polyp Prevention trial): a multicentre, randomised, double-blind, pl...

Por Hull, Mark A, Sprange, Kirsty, Hepburn, Trish, Tan, Wei, Shafayat, Aisha, Rees, Colin J, Clifford, Gayle, Logan, Richard F, Loadman, Paul M, Williams, Elizabeth A, Whitham, Diane, Montgomery, Alan A
Publicado no Lancet (2018)

Development of Novel Tumor-Targeted Theranostic Nanoparticles Activated by Membrane-Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Por Ansari, Celina, Tikhomirov, Grigory A., Hong, Su Hyun, Falconer, Robert A., Loadman, Paul M., Gill, Jason H., Castaneda, Rosalinda, Hazard, Florette K., Tong, Ling, Lenkov, Olga D., Felsher, Dean W., Rao, Jianghong, Daldrup-Link, Heike E.
Publicado em 2013

Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration

Por Al-Saraireh, Yousef M. J., Sutherland, Mark, Springett, Bradley R., Freiberger, Friedrich, Ribeiro Morais, Goreti, Loadman, Paul M., Errington, Rachel J., Smith, Paul J., Fukuda, Minoru, Gerardy-Schahn, Rita, Patterson, Laurence H., Shnyder, Steven D., Falconer, Robert A.
Publicado em 2013

A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival

Por Mohanty, Suchismita, Chen, Zixin, Li, Kai, Morais, Goreti Ribeiro, Klockow, Jessica, Yerneni, Ketan, Pisani, Laura, Chin, Frederick T, Mitra, Siddharta, Cheshier, Samuel, Chang, Edwin, Gambhir, Sanjiv Sam, Rao, Jianghong, Loadman, Paul M., Falconer, Robert A., Daldrup-Link, Heike E
Publicado no Mol Cancer Ther (2017)

Theranostic nanoparticles enhance the response of glioblastomas to radiation

Por Wu, Wei, Klockow, Jessica L., Mohanty, Suchismita, Ku, Kimberly S., Aghighi, Maryam, Melemenidis, Stavros, Chen, Zixin, Li, Kai, Morais, Goreti Ribeiro, Zhao, Ning, Schlegel, Jürgen, Graves, Edward E., Rao, Jianghong, Loadman, Paul M., Falconer, Robert A., Mukherjee, Sudip, Chin, Frederick T., Daldrup-Link, Heike E.
Publicado no Nanotheranostics (2019)

Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicit...

Por Ingram, Nicola, McVeigh, Laura E., Abou-Saleh, Radwa H., Maynard, Juliana, Peyman, Sally A., McLaughlan, James R., Fairclough, Michael, Marston, Gemma, Valleley, Elizabeth M. A., Jimenez-Macias, Jorge L., Charalambous, Antonia, Townley, William, Haddrick, Malcolm, Wierzbicki, Antonia, Wright, Alexander, Volpato, Milène, Simpson, Peter B., Treanor, Darren E., Thomson, Neil H., Loadman, Paul M., Bushby, Richard J., Johnson, Benjamin R.G., Jones, Pamela F., Evans, J. Anthony, Freear, Steven, Markham, Alexander F., Evans, Stephen D., Coletta, P. Louise
Publicado no Theranostics (2020)