FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms

Tumour invasion and metastasis is the most common cause of death from cancer. For epithelial cells to invade surrounding tissues and metastasise, an epithelial-mesenchymal transition (EMT) is required. We have demonstrated that FGFR1 expression is increased in bladder cancer and that activation of F...

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Detalhes bibliográficos
Main Authors: Tomlinson, Darren C., Baxter, Euan W., Loadman, Paul M., Hull, Mark A., Knowles, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373505/
https://ncbi.nlm.nih.gov/pubmed/22701738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038972
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