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FGFR1 promotes proliferation and survival via activation of the MAPK pathway in bladder cancer

Fibroblast growth factor receptors (FGFRs) play key roles in proliferation, differentiation and tumorigenesis. Many urothelial carcinomas (UC) contain activating point mutations or increased expression of FGFR3. However, little is known about the role of other FGFRs. We have examined FGFR expression...

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Detalhes bibliográficos
Main Authors: Tomlinson, Darren C, Lamont, Fiona R, Shnyder, Steve D, Knowles, Margaret A
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737316/
https://ncbi.nlm.nih.gov/pubmed/19458078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2816
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