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Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer
More than 60% of low-grade non-invasive papillary urothelial cell carcinomas contain activating point mutations of FGFR3. The phenotypic consequences of constitutive activation of FGFR3 in bladder cancer have not been elucidated and further studies are required to confirm the consequences of inhibit...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443272/ https://ncbi.nlm.nih.gov/pubmed/17384684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210399 |
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