A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival

Glioblastoma (GBM) has a dismal prognosis. Evidence from preclinical tumor models and human trials indicates the role of GBM initiating cells (GIC) in GBM drug resistance. Here, we propose a new treatment option with tumor enzyme-activatable, combined therapeutic and diagnostic (theranostic) nanopar...

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Publicado no:Mol Cancer Ther
Main Authors: Mohanty, Suchismita, Chen, Zixin, Li, Kai, Morais, Goreti Ribeiro, Klockow, Jessica, Yerneni, Ketan, Pisani, Laura, Chin, Frederick T, Mitra, Siddharta, Cheshier, Samuel, Chang, Edwin, Gambhir, Sanjiv Sam, Rao, Jianghong, Loadman, Paul M., Falconer, Robert A., Daldrup-Link, Heike E
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587386/
https://ncbi.nlm.nih.gov/pubmed/28659432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0022
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