Cyclooxygenase activity mediates colorectal cancer cell resistance to the omega-3 polyunsaturated fatty acid eicosapentaenoic acid

PURPOSE: The naturally-occurring omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) is safe, well-tolerated and inexpensive, making it an attractive anti-cancer intervention. However, EPA has only modest anti-colorectal cancer (CRC) activity, when used alone. Both cyclooxygenase (COX) is...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Volpato, Milene, Ingram, Nicola, Perry, Sarah L, Spencer, Jade, Race, Amanda D, Marshall, Catriona, Hutchinson, John M, Nicolaou, Anna, Loadman, Paul M, Coletta, P Louise, Hull, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870614/
https://ncbi.nlm.nih.gov/pubmed/33040178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04157-2
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