Brk Protects Breast Cancer Cells from Autophagic Cell Death Induced by Loss of Anchorage

Brk, a tyrosine kinase expressed in a majority of breast tumors, but not normal mammary tissue, promotes breast carcinoma cell proliferation. Normal epithelial cells are dependent on cell–cell or cell–matrix interactions for survival and undergo apoptosis after disruption of these interactions. Tumo...

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Detalhes bibliográficos
Main Authors: Harvey, Amanda J., Pennington, Caroline J., Porter, Sarah, Burmi, Rajpal S., Edwards, Dylan R., Court, William, Eccles, Suzanne A., Crompton, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731141/
https://ncbi.nlm.nih.gov/pubmed/19661439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080811
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