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Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption
Cartilage destruction in the arthritides is thought to be mediated by two main enzyme families: the matrix metalloproteinases (MMPs) are responsible for cartilage collagen breakdown, and enzymes from the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) family mediate ca...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174946/ https://ncbi.nlm.nih.gov/pubmed/15899037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1702 |
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