Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP).

Fundamental cellular processes including angiogenesis and cell migration require a proteolytic cascade driven by interactions of membrane-type matrix metalloproteinase 1 (MT1-MMP) and progelatinase A (proMMP-2) that are dependent on the presence of tissue inhibitor of metalloproteinases 2 (TIMP-2)....

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Detalhes bibliográficos
Main Authors: Worley, Joanna R, Thompkins, Philip B, Lee, Meng H, Hutton, Mike, Soloway, Paul, Edwards, Dylan R, Murphy, Gillian, Knäuper, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223438/
https://ncbi.nlm.nih.gov/pubmed/12630911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021573
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