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Regulation of MT1-MMP/MMP-2/TIMP-2 axis in human placenta

Matrix metalloproteinases (MMPs) and specific endogenous tissue inhibitors of metalloproteinases (TIMPs) mediate rupture of the fetal membranes in both physiological and pathological conditions. MMPs and TIMPs are subject to regulation by DNA methylation in human malignancies and pre-eclampsia. To d...

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Bibliografiske detaljer
Udgivet i:J Inflamm Res
Main Authors: Vincent, Zoë L, Mitchell, Murray D, Ponnampalam, Anna P
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599070/
https://ncbi.nlm.nih.gov/pubmed/26491367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S88039
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