The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

The regulation of Ubiquitin (Ub) conjugates generated by the complex network of proteins that promote the mammalian DNA double-strand break (DSB) response is not fully understood. We show here that the Ub protease POH1/rpn11/PSMD14 resident in the 19S proteasome regulatory particle is required for p...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Butler, Laura R, Densham, Ruth M, Jia, Junying, Garvin, Alexander J, Stone, Helen R, Shah, Vandna, Weekes, Daniel, Festy, Frederic, Beesley, James, Morris, Joanna R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463844/
https://ncbi.nlm.nih.gov/pubmed/22909820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.232
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky