Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

Por Bryant, Helen E., Helleday, Thomas
Publicado em 2006

‘Sex’ in the cancer cell

Por Lafta, Inam J., Bryant, Helen E., Goldman, Alastair S. H.
Publicado no Oncotarget (2014)

BRCA2-dependent homologous recombination is required for repair of Arsenite-induced replication lesions in mammalian cells

Por Ying, Songmin, Myers, Katie, Bottomley, Sarah, Helleday, Thomas, Bryant, Helen E.
Publicado em 2009

Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase

Por Gravells, Polly, Grant, Emma, Smith, Kate M., James, Dominic I., Bryant, Helen E.
Publicado no DNA Repair (Amst) (2017)

Altered RECQL5 expression in urothelial bladder carcinoma increases cellular proliferation and makes RECQL5 helicase activity a novel target for chemotherapy

Por Patterson, Karl, Arya, Lovleen, Bottomley, Sarah, Morgan, Susan, Cox, Angela, Catto, James, Bryant, Helen E.
Publicado no Oncotarget (2016)

Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks

Por Saleh-Gohari, Nasrollah, Bryant, Helen E., Schultz, Niklas, Parker, Kayan M., Cassel, Tobias N., Helleday, Thomas
Publicado em 2005

PARP-3 Is a Mono-ADP-ribosylase That Activates PARP-1 in the Absence of DNA

Por Loseva, Olga, Jemth, Ann-Sofie, Bryant, Helen E., Schüler, Herwig, Lehtiö, Lari, Karlberg, Tobias, Helleday, Thomas
Publicado em 2010

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

Por Loseva, Olga, Jemth, Ann-Sofie, Bryant, Helen E., Schüler, Herwig, Lehtiö, Lari, Karlberg, Tobias, Helleday, Thomas
Publicado em 2012

Reduced expression of microRNA-27a modulates cisplatin resistance in bladder cancer by targeting the cystine/glutamate exchanger SLC7A11

Por Drayton, Ross M, Dudziec, Ewa, Peter, Stefan, Bertz, Simone, Hartmann, Arndt, Bryant, Helen E, Catto, James WF
Publicado em 2014

MicroRNA-99a and 100 mediated upregulation of FOXA1 in bladder cancer

Por Drayton, Ross M., Peter, Stefan, Myers, Katie, Miah, Saiful, Dudziec, Ewa, Bryant, Helen E., Catto, James W. F.
Publicado em 2014

Interaction between Herpes Simplex Virus Type 1 IE63 Protein and Cellular Protein p32

Por Bryant, Helen E., Matthews, David A., Wadd, Sarah, Scott, James E., Kean, Joy, Graham, Susan, Russell, William C., Clements, J. Barklie
Publicado em 2000

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination

Por Bryant, Helen E, Petermann, Eva, Schultz, Niklas, Jemth, Ann-Sofie, Loseva, Olga, Issaeva, Natalia, Johansson, Fredrik, Fernandez, Serena, McGlynn, Peter, Helleday, Thomas
Publicado em 2009

Metal Complexes for Two‐Photon Photodynamic Therapy: A Cyclometallated Iridium Complex Induces Two‐Photon Photosensitization of Cancer Cells under Near‐IR Light

Por McKenzie, Luke K., Sazanovich, Igor V., Baggaley, Elizabeth, Bonneau, Mickaële, Guerchais, Véronique, Williams, J. A. Gareth, Weinstein, Julia A., Bryant, Helen E.
Publicado no Chemistry (2016)

Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand

Por Doherty, Rachel E., Sazanovich, Igor V., McKenzie, Luke K., Stasheuski, Alexander S., Coyle, Rachel, Baggaley, Elizabeth, Bottomley, Sarah, Weinstein, Julia A., Bryant, Helen E.
Publicado no Sci Rep (2016)

The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links

Por Al-Minawi, Ali Z., Lee, Yin-Fai, Håkansson, Daniel, Johansson, Fredrik, Lundin, Cecilia, Saleh-Gohari, Nasrollah, Schultz, Niklas, Jenssen, Dag, Bryant, Helen E., Meuth, Mark, Hinz, John M., Helleday, Thomas
Publicado em 2009

Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers

Por Arora, Arvind, Abdel-Fatah, Tarek M.A., Agarwal, Devika, Doherty, Rachel, Croteau, Deborah L., Moseley, Paul M., Hameed, Khalid, Green, Andrew, Aleskandarany, Mohammed A., Rakha, Emad A., Patterson, Karl, Ball, Graham, Chan, Stephen Y.T., Ellis, Ian O., Bohr, Vilhelm A., Bryant, Helen E., Madhusudan, Srinivasan
Publicado no Carcinogenesis (2016)

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Por Eccles, Suzanne A, Aboagye, Eric O, Ali, Simak, Anderson, Annie S, Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P, Brennan, Keith, Brown, Nicola J, Bryant, Helen E, Bundred, Nigel J, Burchell, Joy M, Campbell, Anna M, Carroll, Jason S, Clarke, Robert B, Coles, Charlotte E, Cook, Gary JR, Cox, Angela, Curtin, Nicola J, Dekker, Lodewijk V, dos Santos Silva, Isabel, Duffy, Stephen W, Easton, Douglas F, Eccles, Diana M, Edwards, Dylan R, Edwards, Joanne, Evans, D Gareth, Fenlon, Deborah F, Flanagan, James M, Foster, Claire, Gallagher, William M, Garcia-Closas, Montserrat, Gee, Julia M W, Gescher, Andy J, Goh, Vicky, Groves, Ashley M, Harvey, Amanda J, Harvie, Michelle, Hennessy, Bryan T, Hiscox, Stephen, Holen, Ingunn, Howell, Sacha J, Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S, Jasani, Bharat, Jones, Louise J, Key, Timothy J, Kirwan, Cliona C, Kong, Anthony, Kunkler, Ian H, Langdon, Simon P, Leach, Martin O, Mann, David J, Marshall, John F, Martin, Lesley Ann, Martin, Stewart G, Macdougall, Jennifer E, Miles, David W, Miller, William R, Morris, Joanna R, Moss, Sue M, Mullan, Paul, Natrajan, Rachel, O’Connor, James PB, O’Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D P, Rakha, Emad A, Reed, Elizabeth, Robinson, Simon P, Sahai, Erik, Saxton, John M, Schmid, Peter, Smalley, Matthew J, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H, Tutt, Andrew N J, Velikova, Galina, Walker, Rosemary A, Watson, Christine J, Williams, Kaye J, Young, Leonie S, Thompson, Alastair M
Publicado em 2013