Spontaneous Homologous Recombination Is Induced by Collapsed Replication Forks That Are Caused by Endogenous DNA Single-Strand Breaks

Homologous recombination is vital to repair fatal DNA damage during DNA replication. However, very little is known about the substrates or repair pathways for homologous recombination in mammalian cells. Here, we have compared the recombination products produced spontaneously with those produced fol...

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Detalhes bibliográficos
Main Authors: Saleh-Gohari, Nasrollah, Bryant, Helen E., Schultz, Niklas, Parker, Kayan M., Cassel, Tobias N., Helleday, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Chromosome Structure and Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190269/
https://ncbi.nlm.nih.gov/pubmed/16055725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7158-7169.2005
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