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Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

Cells with non-functional poly(ADP-ribose) polymerase (PARP-1) show increased levels of sister chromatid exchange, suggesting a hyper recombination phenotype in these cells. To further investigate the involvement of PARP-1 in homologous recombination (HR) we investigated how PARP-1 affects nuclear H...

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Autors principals: Schultz, Niklas, Lopez, Elena, Saleh-Gohari, Nasrollah, Helleday, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC212803/
https://ncbi.nlm.nih.gov/pubmed/12930944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg703
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