Expression, purification, crystallization and preliminary X-ray analysis of the PaaI-like thioesterase SAV0944 from Staphylococcus aureus

по Khandokar, Yogesh B., Roman, Noelia, Smith, Kate M., Srivastava, Parul, Forwood, Jade K.
Опубликовано 2014

Specific killing of DNA damage-response deficient cells with inhibitors of poly(ADP-ribose) glycohydrolase

по Gravells, Polly, Grant, Emma, Smith, Kate M., James, Dominic I., Bryant, Helen E.
Опубликовано в: DNA Repair (Amst) (2017)

Radiosensitization with an inhibitor of poly(ADP-ribose) glycohydrolase: A comparison with the PARP1/2/3 inhibitor olaparib

по Gravells, Polly, Neale, James, Grant, Emma, Nathubhai, Amit, Smith, Kate M., James, Dominic I., Bryant, Helen E.
Опубликовано в: DNA Repair (Amst) (2018)

Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase

по Khandokar, Yogesh B., Srivastava, Parul, Cowieson, Nathan, Sarker, Subir, Aragao, David, Das, Shubagata, Smith, Kate M., Raidal, Shane R., Forwood, Jade K.
Опубликовано в: J Biol Chem (2017)

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells

по Zhang, Manqi, Lai, Yanhao, Vasquez, Judy L., James, Dominic I., Smith, Kate M., Waddell, Ian D., Ogilvie, Donald J., Liu, Yuan, Agoulnik, Irina U.
Опубликовано в: Sci Rep (2020)

The Enhanced In Vivo Activity of the Combination of a MEK and a PI3K Inhibitor Correlates with [(18)F]-FLT PET in Human Colorectal Cancer Xenograft Tumour-Bearing Mice

по Haagensen, Emma J., Thomas, Huw D., Wilson, Ian, Harnor, Suzannah J., Payne, Sara L., Rennison, Tommy, Smith, Kate M., Maxwell, Ross J., Newell, David R.
Опубликовано 2013

Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses

по Smith, Kate M., Tsimbalyuk, Sofiya, Edwards, Megan R., Cross, Emily M., Batra, Jyoti, Soares da Costa, Tatiana P., Aragão, David, Basler, Christopher F., Forwood, Jade K.
Опубликовано в: Nat Commun (2018)

Fluoromethylcyclopropylamine derivatives as potential in vivo toxicophores – A cautionary disclosure

по Acton, Ben, Small, Helen F., Smith, Kate M., McGonagle, Alison, Stowell, Alexandra I.J., James, Dominic I., Hamilton, Niall M., Hamilton, Nicola, Hitchin, James R., Hutton, Colin P., Waddell, Ian D., Ogilvie, Donald J., Jordan, Allan M.
Опубликовано в: Bioorg Med Chem Lett (2019)

DNA Replication Vulnerabilities Render Ovarian Cancer Cells Sensitive to Poly(ADP-Ribose) Glycohydrolase Inhibitors

по Pillay, Nisha, Tighe, Anthony, Nelson, Louisa, Littler, Samantha, Coulson-Gilmer, Camilla, Bah, Nourdine, Golder, Anya, Bakker, Bjorn, Spierings, Diana C.J., James, Dominic I., Smith, Kate M., Jordan, Allan M., Morgan, Robert D., Ogilvie, Donald J., Foijer, Floris, Jackson, Dean A., Taylor, Stephen S.
Опубликовано в: Cancer Cell (2019)

Regulation of ALT-associated homology-directed repair by polyADP-ribosylation

по Hoang, Song My, Kaminski, Nicole, Bhargava, Ragini, Barroso-González, Jonathan, Lynskey, Michelle L., García-Expósito, Laura, Roncaioli, Justin L., Wondisford, Anne R., Wallace, Callen T., Watkins, Simon C., James, Dominic I., Waddell, Ian D., Ogilvie, Donald, Smith, Kate M., da Veiga Leprevost, Felipe, Mellacharevu, Dattatreya, Nesvizhskii, Alexey I., Li, Jianfeng, Ray-Gallet, Dominique, Sobol, Robert W., Almouzni, Genevieve, O’Sullivan, Roderick J.
Опубликовано в: Nat Struct Mol Biol (2020)

Poly (ADP) ribose glycohydrolase can be effectively targeted in pancreatic cancer

по Jain, Aditi, Agostini, Lebaron C., McCarthy, Grace A., Chand, Saswati N., Ramirez, AnnJosette, Nevler, Avinoam, Cozzitorto, Joseph, Schultz, Christopher W., Lowder, Cinthya Yabar, Smith, Kate M., Waddell, Ian D., Raitses-Gurevich, Maria, Stossel, Chani, Gorman, Yulia Glick, Atias, Dikla, Yeo, Charles J., Winter, Jordan M., Olive, Kenneth P., Golan, Talia, Pishvaian, Michael J., Ogilvie, Donald, James, Dominic I., Jordan, Allan M., Brody, Jonathan R.
Опубликовано в: Cancer Res (2019)