Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses

Seven human isoforms of importin α mediate nuclear import of cargo in a tissue- and isoform-specific manner. How nuclear import adaptors differentially interact with cargo harbouring the same nuclear localisation signal (NLS) remains poorly understood, as the NLS recognition region is highly conserv...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Smith, Kate M., Tsimbalyuk, Sofiya, Edwards, Megan R., Cross, Emily M., Batra, Jyoti, Soares da Costa, Tatiana P., Aragão, David, Basler, Christopher F., Forwood, Jade K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135763/
https://ncbi.nlm.nih.gov/pubmed/30209309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05928-5
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