Beyond reversal: ubiquitin and ubiquitin-like proteases and the orchestration of the DNA double strand break repair response

por Garvin, Alexander J.
Publicado en Biochem Soc Trans (2019)

SUMO, a small, but powerful, regulator of double-strand break repair

por Garvin, Alexander J., Morris, Joanna R.
Publicado en Philos Trans R Soc Lond B Biol Sci (2017)

GSK3β-SCF(FBXW7α) mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover

por Garvin, Alexander J, Khalaf, Ahmed H A, Rettino, Alessandro, Xicluna, Jerome, Butler, Laura, Morris, Joanna R, Heery, David M, Clarke, Nicole M
Publicado en Nucleic Acids Res (2019)

The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair

por Garvin, Alexander J, Densham, Ruth M, Blair-Reid, Sarah A, Pratt, Kenny M, Stone, Helen R, Weekes, Daniel, Lawrence, Kirsty J, Morris, Joanna R
Publicado 2013

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response

por Butler, Laura R, Densham, Ruth M, Jia, Junying, Garvin, Alexander J, Stone, Helen R, Shah, Vandna, Weekes, Daniel, Festy, Frederic, Beesley, James, Morris, Joanna R
Publicado 2012

The deSUMOylase SENP2 coordinates homologous recombination and nonhomologous end joining by independent mechanisms

por Garvin, Alexander J., Walker, Alexandra K., Densham, Ruth M., Chauhan, Anoop Singh, Stone, Helen R., Mackay, Hannah L., Jamshad, Mohammed, Starowicz, Katarzyna, Daza-Martin, Manuel, Ronson, George E., Lanz, Alexander J., Beesley, James F., Morris, Joanna R.
Publicado en Genes Dev (2019)

Human BRCA1-BARD1 Ubiquitin ligase activity counters chromatin barriers to DNA resection

por Densham, Ruth M, Garvin, Alexander J., Stone, Helen R., Strachan, Joanna, Baldock, Robert A, Daza-Martin, Manuel, Fletcher, Alice, Blair-Reid, Sarah, Beesley, James, Johal, Balraj, Pearl, Laurence H., Neely, Robert, Keep, Nicholas H., Watts, Felicity Z, Morris, Joanna R.
Publicado en Nat Struct Mol Biol (2016)