Inhaled LPS challenges in smokers: a study of pulmonary and systemic effects

Por Aul, Raminder, Armstrong, Jane, Duvoix, Annelyse, Lomas, David, Hayes, Brian, Miller, Bruce E, Jagger, Chris, Singh, Dave
Publicado em 2012

Free Urinary Desmosine and Isodesmosine as COPD Biomarkers: The Relevance of Confounding Factors

Por Ongay, Sara, Sikma, Marijke, Horvatovich, Peter, Hermans, Jos, Miller, Bruce E., ten Hacken, Nick H.T., Bischoff, Rainer
Publicado no Chronic Obstr Pulm Dis (2016)

COPD association and repeatability of blood biomarkers in the ECLIPSE cohort

Por Dickens Jennifer A, Miller Bruce E, Edwards Lisa D, Silverman Edwin K, Lomas David A, Tal-Singer Ruth
Publicado em 2011-11-01

COPD association and repeatability of blood biomarkers in the ECLIPSE cohort

Por Dickens, Jennifer A, Miller, Bruce E, Edwards, Lisa D, Silverman, Edwin K, Lomas, David A, Tal-Singer, Ruth
Publicado em 2011

Assessment of potential drug interactions by characterization of human drug metabolism pathways using non-invasive bile sampling

Por Bloomer, Jackie C, Nash, Mike, Webb, Alison, Miller, Bruce E, Lazaar, Aili L, Beaumont, Claire, Guiney, William J
Publicado em 2013

Multiple biomarkers predict disease severity, progression and mortality in COPD

Por Zemans, Rachel L., Jacobson, Sean, Keene, Jason, Kechris, Katerina, Miller, Bruce E., Tal-Singer, Ruth, Bowler, Russell P.
Publicado no Respir Res (2017)

The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

Por Miller, Bruce E., Mistry, Sunil, Smart, Kevin, Connolly, Paul, Carpenter, Donald C., Cooray, Hiran, Bloomer, Jackie C., Tal-Singer, Ruth, Lazaar, Aili L.
Publicado no BMC Pharmacol Toxicol (2015)

The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers

Por Miller, Bruce E., Smart, Kevin, Mistry, Sunil, Ambery, Claire L., Bloomer, Jackie C., Connolly, Paul, Sanderson, Dominic, Shreeves, Trevor, Smith, Rachel, Lazaar, Aili L.
Publicado em 2014

High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study

Por Sand, Jannie M. B., Leeming, Diana J., Byrjalsen, Inger, Bihlet, Asger R., Lange, Peter, Tal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten A., Vestbo, Jørgen
Publicado no Respir Res (2016)

The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease

Por Obeidat, Ma’en, Ding, Xiaoting, Fishbane, Nick, Hollander, Zsuzsanna, Ng, Raymond T., McManus, Bruce, Tebbutt, Scott J., Miller, Bruce E., Rennard, Stephen, Paré, Peter D., Sin, Don D.
Publicado no Nicotine Tob Res (2016)

The Effect of Statins on Blood Gene Expression in COPD

Por Obeidat, Ma’en, Fishbane, Nick, Nie, Yunlong, Chen, Virginia, Hollander, Zsuzsanna, Tebbutt, Scott J., Bossé, Yohan, Ng, Raymond T., Miller, Bruce E., McManus, Bruce, Rennard, Stephen, Paré, Peter D., Sin, Don D.
Publicado no PLoS One (2015)

Characterisation of COPD heterogeneity in the ECLIPSE cohort

Por Agusti Alvar, Calverley Peter MA, Celli Bartolome, Coxson Harvey O, Edwards Lisa D, Lomas David A, MacNee William, Miller Bruce E, Rennard Steve, Silverman Edwin K, Tal-Singer Ruth, Wouters Emiel, Yates Julie C, Vestbo Jørgen
Publicado em 2010-09-01

Characterisation of COPD heterogeneity in the ECLIPSE cohort

Por Agusti, Alvar, Calverley, Peter MA, Celli, Bartolome, Coxson, Harvey O, Edwards, Lisa D, Lomas, David A, MacNee, William, Miller, Bruce E, Rennard, Steve, Silverman, Edwin K, Tal-Singer, Ruth, Wouters, Emiel, Yates, Julie C, Vestbo, Jørgen
Publicado em 2010

A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease

Por Menche, Jörg, Sharma, Amitabh, Cho, Michael H, Mayer, Ruth J, Rennard, Stephen I, Celli, Bartolome, Miller, Bruce E, Locantore, Nick, Tal-Singer, Ruth, Ghosh, Soumitra, Larminie, Chris, Bradley, Glyn, Riley, John H, Agusti, Alvar, Silverman, Edwin K, Barabási, Albert-László
Publicado em 2014

An Aberrant Leukotriene A(4) Hydrolase–Proline-Glycine-Proline Pathway in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Por Wells, J. Michael, O’Reilly, Philip J., Szul, Tomasz, Sullivan, Daniel I., Handley, Guy, Garrett, Chris, McNicholas, Carmel M., Roda, Mojtaba Abdul, Miller, Bruce E., Tal-Singer, Ruth, Gaggar, Amit, Rennard, Stephen I., Jackson, Patricia L., Blalock, J. Edwin
Publicado no Am J Respir Crit Care Med (2014)

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

Por Obeidat, Ma’en, Nie, Yunlong, Chen, Virginia, Shannon, Casey P., Andiappan, Anand Kumar, Lee, Bernett, Rotzschke, Olaf, Castaldi, Peter J., Hersh, Craig P., Fishbane, Nick, Ng, Raymond T., McManus, Bruce, Miller, Bruce E., Rennard, Stephen, Paré, Peter D., Sin, Don D.
Publicado no Respir Res (2017)

Serum PARC/CCL-18 Concentrations and Health Outcomes in Chronic Obstructive Pulmonary Disease

Por Sin, Don D., Miller, Bruce E., Duvoix, Annelyse, Man, S. F. Paul, Zhang, Xuekui, Silverman, Edwin K., Connett, John E., Anthonisen, Nicholas A., Wise, Robert A., Tashkin, Donald, Celli, Bartolome R., Edwards, Lisa D., Locantore, Nicholas, MacNee, William, Tal-Singer, Ruth, Lomas, David A.
Publicado em 2011

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype

Por Agustí, Alvar, Edwards, Lisa D., Rennard, Stephen I., MacNee, William, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Lomas, David A., Calverley, Peter M. A., Wouters, Emiel, Crim, Courtney, Yates, Julie C., Silverman, Edwin K., Coxson, Harvey O., Bakke, Per, Mayer, Ruth J., Celli, Bartolome
Publicado em 2012

Genome-Wide Association Analysis of Blood Biomarkers in Chronic Obstructive Pulmonary Disease

Por Kim, Deog Kyeom, Cho, Michael H., Hersh, Craig P., Lomas, David A., Miller, Bruce E., Kong, Xiangyang, Bakke, Per, Gulsvik, Amund, Agustí, Alvar, Wouters, Emiel, Celli, Bartolome, Coxson, Harvey, Vestbo, Jørgen, MacNee, William, Yates, Julie C., Rennard, Stephen, Litonjua, Augusto, Qiu, Weiliang, Beaty, Terri H., Crapo, James D., Riley, John H., Tal-Singer, Ruth, Silverman, Edwin K.
Publicado em 2012

Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study

Por O’Neal, Wanda K, Anderson, Wayne, Basta, Patricia V, Carretta, Elizabeth E, Doerschuk, Claire M, Barr, R Graham, Bleecker, Eugene R, Christenson, Stephanie A, Curtis, Jeffrey L, Han, Meilan K, Hansel, Nadia N, Kanner, Richard E, Kleerup, Eric C, Martinez, Fernando J, Miller, Bruce E, Peters, Stephen P, Rennard, Stephen I, Scholand, Mary Beth, Tal-Singer, Ruth, Woodruff, Prescott G, Couper, David J, Davis, Sonia M
Publicado em 2014