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High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study

BACKGROUND: There is a need to identify individuals with COPD at risk for disease progression and mortality. Lung tissue remodeling is associated with the release of extracellular matrix (ECM) fragments into the peripheral circulation. We hypothesized that ECM remodeling was associated with mortalit...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Sand, Jannie M. B., Leeming, Diana J., Byrjalsen, Inger, Bihlet, Asger R., Lange, Peter, Tal-Singer, Ruth, Miller, Bruce E., Karsdal, Morten A., Vestbo, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050854/
https://ncbi.nlm.nih.gov/pubmed/27716343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0440-6
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