Elevated Airway Purines in COPD

Por Esther, Charles R., Lazaar, Aili L., Bordonali, Elena, Qaqish, Bahjat, Boucher, Richard C.
Publicado em 2011

The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma

Por Macdonald Alex J, Petavy Frank, Singh Dave, Lazaar Aili L, O'Connor Brian J
Publicado em 2010-03-01

The inhaled phosphodiesterase 4 inhibitor GSK256066 reduces allergen challenge responses in asthma

Por Singh, Dave, Petavy, Frank, Macdonald, Alex J, Lazaar, Aili L, O'Connor, Brian J
Publicado em 2010

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

Por Lazaar, Aili L, Sweeney, Lisa E, MacDonald, Alexander J, Alexis, Neil E, Chen, Chao, Tal-Singer, Ruth
Publicado em 2011

Assessment of potential drug interactions by characterization of human drug metabolism pathways using non-invasive bile sampling

Por Bloomer, Jackie C, Nash, Mike, Webb, Alison, Miller, Bruce E, Lazaar, Aili L, Beaumont, Claire, Guiney, William J
Publicado em 2013

The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756) − a selective CXCR2 antagonist − in healthy adult subjects

Por Miller, Bruce E., Mistry, Sunil, Smart, Kevin, Connolly, Paul, Carpenter, Donald C., Cooray, Hiran, Bloomer, Jackie C., Tal-Singer, Ruth, Lazaar, Aili L.
Publicado no BMC Pharmacol Toxicol (2015)

The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers

Por Miller, Bruce E., Smart, Kevin, Mistry, Sunil, Ambery, Claire L., Bloomer, Jackie C., Connolly, Paul, Sanderson, Dominic, Shreeves, Trevor, Smith, Rachel, Lazaar, Aili L.
Publicado em 2014

Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers

Por Yang, Lucy, Cheriyan, Joseph, Gutterman, David D., Mayer, Ruth J., Ament, Zsuzsanna, Griffin, Jules L., Lazaar, Aili L., Newby, David E., Tal-Singer, Ruth, Wilkinson, Ian B.
Publicado no Chest (2017)

Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor

Por Lazaar, Aili L., Yang, Lucy, Boardley, Rebecca L., Goyal, Navin S., Robertson, Jonathan, Baldwin, Sandra J., Newby, David E., Wilkinson, Ian B., Tal‐Singer, Ruth, Mayer, Ruth J., Cheriyan, Joseph
Publicado no Br J Clin Pharmacol (2016)

A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome

Por Khan, Akram, Benthin, Cody, Zeno, Brian, Albertson, Timothy E., Boyd, John, Christie, Jason D., Hall, Richard, Poirier, Germain, Ronco, Juan J., Tidswell, Mark, Hardes, Kelly, Powley, William M., Wright, Tracey J., Siederer, Sarah K., Fairman, David A., Lipson, David A., Bayliffe, Andrew I., Lazaar, Aili L.
Publicado no Crit Care (2017)