Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial

Por Betts, Joanna C, Mayer, Ruth J, Tal-Singer, Ruth, Warnock, Linda, Clayton, Chris, Bates, Stewart, Hoffman, Bryan E, Larminie, Christopher, Singh, Dave
Publicado no Pharmacol Res Perspect (2015)

Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers

Por Yang, Lucy, Cheriyan, Joseph, Gutterman, David D., Mayer, Ruth J., Ament, Zsuzsanna, Griffin, Jules L., Lazaar, Aili L., Newby, David E., Tal-Singer, Ruth, Wilkinson, Ian B.
Publicado no Chest (2017)

Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor

Por Lazaar, Aili L., Yang, Lucy, Boardley, Rebecca L., Goyal, Navin S., Robertson, Jonathan, Baldwin, Sandra J., Newby, David E., Wilkinson, Ian B., Tal‐Singer, Ruth, Mayer, Ruth J., Cheriyan, Joseph
Publicado no Br J Clin Pharmacol (2016)

A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease

Por Menche, Jörg, Sharma, Amitabh, Cho, Michael H, Mayer, Ruth J, Rennard, Stephen I, Celli, Bartolome, Miller, Bruce E, Locantore, Nick, Tal-Singer, Ruth, Ghosh, Soumitra, Larminie, Chris, Bradley, Glyn, Riley, John H, Agusti, Alvar, Silverman, Edwin K, Barabási, Albert-László
Publicado em 2014

Persistent Systemic Inflammation is Associated with Poor Clinical Outcomes in COPD: A Novel Phenotype

Por Agustí, Alvar, Edwards, Lisa D., Rennard, Stephen I., MacNee, William, Tal-Singer, Ruth, Miller, Bruce E., Vestbo, Jørgen, Lomas, David A., Calverley, Peter M. A., Wouters, Emiel, Crim, Courtney, Yates, Julie C., Silverman, Edwin K., Coxson, Harvey O., Bakke, Per, Mayer, Ruth J., Celli, Bartolome
Publicado em 2012

Pharmacological Characterization of a Novel ENaCα siRNA (GSK2225745) With Potential for the Treatment of Cystic Fibrosis

Por Clark, Kenneth L, Hughes, Stephen A, Bulsara, Pallav, Coates, Jill, Moores, Kitty, Parry, Joel, Carr, Michael, Mayer, Ruth J, Wilson, Paul, Gruenloh, Chris, Levin, Daren, Darton, Jill, Weber, Wolf-Michael, Sobczak, Katja, Gill, Deborah R, Hyde, Stephen C, Davies, Lee A, Pringle, Ian A, Sumner-Jones, Stephanie G, Jadhav, Vasant, Jamison, Sharon, Strapps, Walter R, Pickering, Victoria, Edbrooke, Mark R
Publicado em 2013