Seeking Ligand Bias: Assessing GPCR Coupling to Beta-Arrestins for Drug Discovery

Por Bohn, Laura M., McDonald, Patricia H.
Publicado em 2010

Cultural Comparison of Chronic Conditions, Functional Status, and Acceptance in Older African-American and White Adults

Por McDonald, Patricia E., Zauszniewski, Jaclene A., Bekhet, Abir K.
Publicado em 2010

Psychometric Properties of a Measure of Acceptance of Long-Standing Health Problems

Por McDonald, Patricia E., Zauszniewski, Jaclene A., Bekhet, Abir K.
Publicado em 2011

Melanocortin-3 Receptors and Metabolic Homeostasis

Por Begriche, Karima, Girardet, Clemencé, McDonald, Patricia, Butler, Andrew A.
Publicado em 2013

Development of a High-Throughput Screening–Compatible Cell-Based Functional Assay to Identify Small Molecule Probes of the Galanin 3 Receptor (GalR3)

Por Robinson, James, Smith, Anthony, Sturchler, Emmanuel, Tabrizifard, Sahba, Kamenecka, Theodore, McDonald, Patricia
Publicado em 2013

Development of an HTS-Compatible Assay for the Discovery of ASK1 Signalosome Inhibitors Using AlphaScreen Technology

Por Sturchler, Emmanuel, Chen, Weimin, Spicer, Timothy, Hodder, Peter, McDonald, Patricia, Duckett, Derek
Publicado em 2014

Heme-Oxygenase-1 Induced Protection Against Hypoxia/Reoxygenation is Dependent on Biliverdin Reductase and its Interaction with PI3K/Akt Pathway

Por Pachori, Alok S., Smith, Anthony, McDonald, Patricia, Zhang, Lunan, Dzau, Victor J., Melo, Luis G.
Publicado em 2007

The Effect of Acceptance Training on Psychological and Physical Health Outcomes in Elders with Chronic Conditions

Por McDonald, Patricia E., Zauszniewski, Jaclene A., Bekhet, Abir K., DeHelian, Laura, Morris, Diana L.
Publicado em 2011

The Discovery of Indole Full Agonists of the Neurotensin Receptor 1 (NTSR1)

Por Di Fruscia, Paolo, He, Yuanjun, Koenig, Marcel, Tabrizifard, Sahba, Nieto, Ainhoa, McDonald, Patricia H., Kamenecka, Theodore M.
Publicado em 2014

Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison

Por Dabul, Samalia, Bathgate-Siryk, Ashley, Valero, Thairy Reyes, Jafferjee, Malika, Sturchler, Emmanuel, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Publicado no Sci Rep (2015)

Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production

Por Valero, Thairy Reyes, Sturchler, Emmanuel, Jafferjee, Malika, Rengo, Giuseppe, Magafa, Vassiliki, Cordopatis, Paul, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Publicado no Pharmacol Res Perspect (2016)

Selective and Brain Penetrant Neuropeptide Y Y2 Receptor Antagonists Discovered by Whole-Cell High-Throughput Screening

Por Brothers, Shaun P., Saldanha, S. Adrian, Spicer, Timothy P., Cameron, Michael, Mercer, Becky A., Chase, Peter, McDonald, Patricia, Wahlestedt, Claes, Hodder, Peter S.
Publicado em 2010

GABA(B) receptor allosteric modulators exhibit pathway‐dependent and species‐selective activity

Por Sturchler, Emmanuel, Li, Xia, de Lourdes Ladino, Maria, Kaczanowska, Kasia, Cameron, Michael, Griffin, Patrick R., Finn, M. G., Markou, Athina, McDonald, Patricia
Publicado no Pharmacol Res Perspect (2017)

Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer

Por Akhter, Shahab A., Skaer, Christine A., Kypson, Alan P., McDonald, Patricia H., Peppel, Karsten C., Glower, Donald D., Lefkowitz, Robert J., Koch, Walter J.
Publicado em 1997

Disubstituted piperidines as potent Orexin (hypocretin) receptor antagonists

Por Jiang, Rong, Song, Xinyi, Bali, Purva, Smith, Anthony, Bayona, Claudia Ruiz, Lin, Li, Cameron, Michael D., McDonald, Patricia H., Kenny, Paul J., Kamenecka, Theodore M.
Publicado em 2012

Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary β(2)-adrenergic receptor gene delivery

Por Maurice, John P., Hata, Jonathan A., Shah, Ashish S., White, David C., McDonald, Patricia H., Dolber, Paul C., Wilson, Katrina H., Lefkowitz, Robert J., Glower, Donald D., Koch, Walter J.
Publicado em 1999

Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects

Por Zhang, Hongkai, Sturchler, Emmanuel, Zhu, Jiang, Nieto, Ainhoa, Cistrone, Philip A., Xie, Jia, He, LinLing, Yea, Kyungmoo, Jones, Teresa, Turn, Rachel, Di Stefano, Peter S., Griffin, Patrick R., Dawson, Philip E., McDonald, Patricia H., Lerner, Richard A.
Publicado no Nat Commun (2015)

Structural mechanism of ligand activation in human calcium-sensing receptor

Por Geng, Yong, Mosyak, Lidia, Kurinov, Igor, Zuo, Hao, Sturchler, Emmanuel, Cheng, Tat Cheung, Subramanyam, Prakash, Brown, Alice P, Brennan, Sarah C, Mun, Hee-chang, Bush, Martin, Chen, Yan, Nguyen, Trang X, Cao, Baohua, Chang, Donald D, Quick, Matthias, Conigrave, Arthur D, Colecraft, Henry M, McDonald, Patricia, Fan, Qing R
Publicado no eLife (2016)

EMOTIONAL REACTIONS TO PAIN PREDICT PSYCHOLOGICAL DISTRESS IN ADULT PATIENTS WITH SICKLE CELL DISEASE (SCD)

Por EDWARDS, CHRISTOPHER L., KILLOUGH, ALVIN, WOOD, MARY, DOYLE, TODD, FELIU, MIRIAM, BARKER, CAMELA S., UPPAL, PRIYANKA, DeCASTRO, LAURA, WELLINGTON, CHANTÉ, WHITFIELD, KEITH E., TRAMBADIA, JAY, GUINYARD, DARIENE, MUHAMMAD, MALIK, O’GARO, KEISHA-GAYE N., MORGAN, KAI, EDWARDS ALESII, LEKISHA Y., BYRD, GOLDIE S., McCABE, MELANIE, GOLI, VEERAINDAR, KEYS, ABIGAIL, HILL, LABARRON, COLLINS-McNEIL, JANICE, McDONALD, PATRICIA, SCHMECHEL, DONALD E., ROBINSON, ELWOOD
Publicado no Int J Psychiatry Med (2014)