Increased Receptor Stimulation Elicits Differential Calcium-sensing Receptor(T888) Dephosphorylation

Por McCormick, Wanda D., Atkinson-Dell, Rebecca, Campion, Katherine L., Mun, Hee-Chang, Conigrave, Arthur D., Ward, Donald T.
Publicado em 2010

Allosteric activation of the extracellular Ca(2+)-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation

Por Lee, Heather J., Mun, Hee-Chang, Lewis, Narelle C., Crouch, Michael F., Culverston, Emma L., Mason, Rebecca S., Conigrave, Arthur D.
Publicado em 2007

Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

Por Centeno, Patricia P., Herberger, Amanda, Mun, Hee-Chang, Tu, Chialing, Nemeth, Edward F., Chang, Wenhan, Conigrave, Arthur D., Ward, Donald T.
Publicado no Nat Commun (2019)

Allosteric Modulation of the Calcium-sensing Receptor by γ-Glutamyl Peptides: INHIBITION OF PTH SECRETION, SUPPRESSION OF INTRACELLULAR cAMP LEVELS, AND A COMMON MECHANISM OF ACTIO...

Por Broadhead, Geoffrey K., Mun, Hee-chang, Avlani, Vimesh A., Jourdon, Orane, Church, W. Bret, Christopoulos, Arthur, Delbridge, Leigh, Conigrave, Arthur D.
Publicado em 2011

Dual Action Calcium-Sensing Receptor Modulator Unmasks Novel Mode-Switching Mechanism

Por Gregory, Karen J., Kufareva, Irina, Keller, Andrew N., Khajehali, Elham, Mun, Hee-Chang, Goolam, Mahvash A., Mason, Rebecca S., Capuano, Ben, Conigrave, Arthur D., Christopoulos, Arthur, Leach, Katie
Publicado no ACS Pharmacol Transl Sci (2018)

Pathophysiologic Changes in Extracellular pH Modulate Parathyroid Calcium-Sensing Receptor Activity and Secretion via a Histidine-Independent Mechanism

Por Campion, Katherine L., McCormick, Wanda D., Warwicker, Jim, Khayat, Mohd Ezuan Bin, Atkinson-Dell, Rebecca, Steward, Martin C., Delbridge, Leigh W., Mun, Hee-Chang, Conigrave, Arthur D., Ward, Donald T.
Publicado no J Am Soc Nephrol (2015)

Structural mechanism of ligand activation in human calcium-sensing receptor

Por Geng, Yong, Mosyak, Lidia, Kurinov, Igor, Zuo, Hao, Sturchler, Emmanuel, Cheng, Tat Cheung, Subramanyam, Prakash, Brown, Alice P, Brennan, Sarah C, Mun, Hee-chang, Bush, Martin, Chen, Yan, Nguyen, Trang X, Cao, Baohua, Chang, Donald D, Quick, Matthias, Conigrave, Arthur D, Colecraft, Henry M, McDonald, Patricia, Fan, Qing R
Publicado no eLife (2016)