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Allosteric activation of the extracellular Ca(2+)-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation

The calcium-sensing receptor (CaR) mediates feedback control of Ca(2+)(o) (extracellular Ca(2+)) concentration. Although the mechanisms are not fully understood, the CaR couples to several important intracellular signalling enzymes, including PI-PLC (phosphoinositide-specific phospholipase C), leadi...

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Dettagli Bibliografici
Autori principali: Lee, Heather J., Mun, Hee-Chang, Lewis, Narelle C., Crouch, Michael F., Culverston, Emma L., Mason, Rebecca S., Conigrave, Arthur D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868832/
https://ncbi.nlm.nih.gov/pubmed/17212589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061826
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