Ion Channel Engineering: Perspectives and Strategies

Por Subramanyam, Prakash, Colecraft, Henry M.
Publicado no J Mol Biol (2014)

Similar molecular determinants on Rem mediate two distinct modes of inhibition of Ca(V)1.2 channels

Por Puckerin, Akil A., Chang, Donald D., Subramanyam, Prakash, Colecraft, Henry M.
Publicado no Channels (Austin) (2016)

LQT1 mutations in KCNQ1 C-terminus assembly domain suppress I(Ks) using different mechanisms

Por Aromolaran, Ademuyiwa S., Subramanyam, Prakash, Chang, Donald D., Kobertz, William R., Colecraft, Henry M.
Publicado no Cardiovasc Res (2014)

Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing

Por Subramanyam, Prakash, Chang, Donald D., Fang, Kun, Xie, Wenjun, Marks, Andrew R., Colecraft, Henry M.
Publicado em 2013

Reciprocal Interactions Regulate Targeting of Calcium Channel β Subunits and Membrane Expression of α(1) Subunits in Cultured Hippocampal Neurons

Por Obermair, Gerald J., Schlick, Bettina, Di Biase, Valentina, Subramanyam, Prakash, Gebhart, Mathias, Baumgartner, Sabine, Flucher, Bernhard E.
Publicado em 2010

Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia

Por Joseph, Leroy C., Subramanyam, Prakash, Radlicz, Christopher, Trent, Chad M., Iyer, Vivek, Colecraft, Henry M., Morrow, John P.
Publicado no Heart Rhythm (2016)

Activity and calcium regulate nuclear targeting of the calcium channel β(4b) subunit in nerve and muscle cells

Por Subramanyam, Prakash, Obermair, Gerald J., Baumgartner, Sabine, Gebhart, Mathias, Striessnig, Jörg, Kaufmann, Walter A., Geley, Stephan, Flucher, Bernhard E.
Publicado em 2009

Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

Por Joseph, Leroy C., Barca, Emanuele, Subramanyam, Prakash, Komrowski, Michael, Pajvani, Utpal, Colecraft, Henry M., Hirano, Michio, Morrow, John P.
Publicado no PLoS One (2016)

Correction: Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

Por Joseph, Leroy C., Barca, Emanuele, Subramanyam, Prakash, Komrowski, Michael, Pajvani, Utpal, Colecraft, Henry M., Hirano, Michio, Morrow, John P.
Publicado no PLoS One (2017)

Serotonin reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local antiresorptive effect

Por Ortuño, María José, Robinson, Samuel T., Subramanyam, Prakash, Paone, Riccardo, Huang, Yung-yu, Guo, X. Edward, Colecraft, Henry M., Mann, J. John, Ducy, Patricia
Publicado no Nat Med (2016)

Cardiac Ca(V)1.2 channels require β subunits for β-adrenergic–mediated modulation but not trafficking

Por Yang, Lin, Katchman, Alexander, Kushner, Jared, Kushnir, Alexander, Zakharov, Sergey I., Chen, Bi-xing, Shuja, Zunaira, Subramanyam, Prakash, Liu, Guoxia, Papa, Arianne, Roybal, Daniel, Pitt, Geoffrey S., Colecraft, Henry M., Marx, Steven O.
Publicado no J Clin Invest (2019)

Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function

Por Joseph, Leroy C., Kokkinaki, Dimitra, Valenti, Mesele-Christina, Kim, Grace J., Barca, Emanuele, Tomar, Dhanendra, Hoffman, Nicholas E., Subramanyam, Prakash, Colecraft, Henry M., Hirano, Michio, Ratner, Adam J., Madesh, Muniswamy, Drosatos, Konstantinos, Morrow, John P.
Publicado no JCI Insight (2017)

Dietary Saturated Fat Promotes Arrhythmia by Activating NADPH Oxidase 2 (NOX2)

Por Joseph, Leroy C., Avula, Uma Mahesh R., Wan, Elaine Y., Reyes, Michael V., Lakkadi, Kundanika R., Subramanyam, Prakash, Nakanishi, Koki, Homma, Shunichi, Muchir, Antoine, Pajvani, Utpal B., Thorp, Edward B., Reiken, Steven R., Marks, Andrew R., Colecraft, Henry M., Morrow, John P.
Publicado no Circ Arrhythm Electrophysiol (2019)

Structural mechanism of ligand activation in human calcium-sensing receptor

Por Geng, Yong, Mosyak, Lidia, Kurinov, Igor, Zuo, Hao, Sturchler, Emmanuel, Cheng, Tat Cheung, Subramanyam, Prakash, Brown, Alice P, Brennan, Sarah C, Mun, Hee-chang, Bush, Martin, Chen, Yan, Nguyen, Trang X, Cao, Baohua, Chang, Donald D, Quick, Matthias, Conigrave, Arthur D, Colecraft, Henry M, McDonald, Patricia, Fan, Qing R
Publicado no eLife (2016)