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Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
Manipulating expression of large genes (>6 kb) in adult cardiomyocytes is challenging because these cells are only efficiently transduced by viral vectors with a 4–7 kb packaging capacity. This limitation impedes understanding structure–function mechanisms of important proteins in heart. L-type c...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780916/ https://ncbi.nlm.nih.gov/pubmed/24003157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308161110 |
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