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Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production

The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion induction, a steroid hormone that contributes to the pathology of postmyocardial infarction (MI) heart failure (HF), is mediated by both G(q/11) proteins and β‐arrestins, both of which couple to the AngII ty...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Valero, Thairy Reyes, Sturchler, Emmanuel, Jafferjee, Malika, Rengo, Giuseppe, Magafa, Vassiliki, Cordopatis, Paul, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804318/
https://ncbi.nlm.nih.gov/pubmed/27069636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.226
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