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An adrenal β-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo

Aldosterone produces a multitude of effects in vivo, including promotion of postmyocardial infarction adverse cardiac remodeling and heart failure progression. It is produced and secreted by the adrenocortical zona glomerulosa (AZG) cells after angiotensin II (AngII) activation of AngII type 1 recep...

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Detalhes bibliográficos
Main Authors: Lymperopoulos, Anastasios, Rengo, Giuseppe, Zincarelli, Carmela, Kim, Jihee, Soltys, Stephen, Koch, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666999/
https://ncbi.nlm.nih.gov/pubmed/19289825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811706106
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