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Adrenal Beta-Arrestin 1 Inhibition In Vivo Attenuates Post-Myocardial Infarction Progression to Heart Failure and Adverse Remodeling Via Reduction of Circulating Aldosterone Levels

OBJECTIVES: We investigated whether adrenal beta-arrestin 1 (βarr1)-mediated aldosterone production plays any role in post-myocardial infarction (MI) heart failure (HF) progression. BACKGROUND: Heart failure represents 1 of the most significant health problems worldwide, and new and innovative treat...

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Detalhes bibliográficos
Main Authors: Lymperopoulos, Anastasios, Rengo, Giuseppe, Zincarelli, Carmela, Kim, Jihee, Koch, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3087631/
https://ncbi.nlm.nih.gov/pubmed/21232674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.08.635
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