GRK2 Up-Regulation Creates a Positive Feedback Loop for Catecholamine Production in Chromaffin Cells

Elevated sympathetic nervous system (SNS) activity aggravates several diseases, including heart failure. The molecular cause(s) underlying this SNS hyperactivity are not known. We have previously uncovered a neurohormonal mechanism, operating in adrenomedullary chromaffin cells, by which circulating...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Endocrinol
Hauptverfasser: Jafferjee, Malika, Reyes Valero, Thairy, Marrero, Christine, McCrink, Katie A., Brill, Ava, Lymperopoulos, Anastasios
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414648/
https://ncbi.nlm.nih.gov/pubmed/26849467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1305
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