GRK2 Up-Regulation Creates a Positive Feedback Loop for Catecholamine Production in Chromaffin Cells

Elevated sympathetic nervous system (SNS) activity aggravates several diseases, including heart failure. The molecular cause(s) underlying this SNS hyperactivity are not known. We have previously uncovered a neurohormonal mechanism, operating in adrenomedullary chromaffin cells, by which circulating...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Jafferjee, Malika, Reyes Valero, Thairy, Marrero, Christine, McCrink, Katie A., Brill, Ava, Lymperopoulos, Anastasios
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414648/
https://ncbi.nlm.nih.gov/pubmed/26849467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1305
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