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Structure–activity relationship study of angiotensin II analogs in terms of β‐arrestin‐dependent signaling to aldosterone production

The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion induction, a steroid hormone that contributes to the pathology of postmyocardial infarction (MI) heart failure (HF), is mediated by both G(q/11) proteins and β‐arrestins, both of which couple to the AngII ty...

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Publicado en:Pharmacol Res Perspect
Autores principales: Valero, Thairy Reyes, Sturchler, Emmanuel, Jafferjee, Malika, Rengo, Giuseppe, Magafa, Vassiliki, Cordopatis, Paul, McDonald, Patricia, Koch, Walter J., Lymperopoulos, Anastasios
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804318/
https://ncbi.nlm.nih.gov/pubmed/27069636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.226
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