Prion propagation in vitro: are we there yet?

по Ryou, Chongsuk, Mays, Charles E.
Опубликовано 2008

Plasminogen: A cellular protein cofactor for PrP(Sc) propagation

по Mays, Charles E, Ryou, Chongsuk
Опубликовано 2011

Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source

по Mays, Charles E., Titlow, William, Seward, Tanya, Telling, Glenn C., Ryou, Chongsuk
Опубликовано 2009

The suppression of prion propagation using poly-L-lysine by targeting plasminogen that stimulates prion protein conversion

по Ryou, Chongsuk, Titlow, William B., Mays, Charles E., Bae, Younsoo, Kim, Sehun
Опубликовано 2011

Application of PMCA to screen for prion infection in a human cell line used to produce biological therapeutics

по Lyon, Adam, Mays, Charles E., Borriello, Frank, Telling, Glenn C., Soto, Claudio, Pritzkow, Sandra
Опубликовано в: Sci Rep (2019)

Proteasomal Inhibition Redirects the PrP-Like Shadoo Protein to the Nucleus

по Kang, Sang-Gyun, Mays, Charles E., Daude, Nathalie, Yang, Jing, Kar, Satyabrata, Westaway, David
Опубликовано в: Mol Neurobiol (2019)

Modeling amyloid beta and tau pathology in human cerebral organoids

по Gonzalez, Cesar, Armijo, Enrique, Bravo-Alegria, Javiera, Becerra-Calixto, Andrea, Mays, Charles E., Soto, Claudio
Опубликовано в: Mol Psychiatry (2018)

Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein

по Stocki, Pawel, Sawicki, Maxime, Mays, Charles E., Hong, Seo Jung, Chapman, Daniel C., Westaway, David, Williams, David B.
Опубликовано в: Mol Biol Cell (2016)

Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrP(Sc) Species

по Mays, Charles E., van der Merwe, Jacques, Kim, Chae, Haldiman, Tracy, McKenzie, Debbie, Safar, Jiri G., Westaway, David
Опубликовано в: J Virol (2015)

Infectious Prions Accumulate to High Levels in Non Proliferative C2C12 Myotubes

по Herbst, Allen, Banser, Pamela, Velasquez, Camilo Duque, Mays, Charles E., Sim, Valerie L., Westaway, David, Aiken, Judd M., McKenzie, Debbie
Опубликовано 2013

In Vitro Amplification of Misfolded Prion Protein Using Lysate of Cultured Cells

по Mays, Charles E., Yeom, Jihyun, Kang, Hae-Eun, Bian, Jifeng, Khaychuk, Vadim, Kim, Younghwan, Bartz, Jason C., Telling, Glenn C., Ryou, Chongsuk
Опубликовано 2011

CRBL cells: Establishment, characterization and susceptibility to prion infection

по Mays, Charles E., Kang, Hae-Eun, Kim, Younghwan, Shim, Sung Han, Bang, Ji-Eun, Woo, Hee-Jong, Cho, Youl-Hee, Kim, Jae-Beom, Ryou, Chongsuk
Опубликовано 2008

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70)

по Mays, Charles E., Armijo, Enrique, Morales, Rodrigo, Kramm, Carlos, Flores, Andrea, Tiwari, Anjana, Bian, Jifeng, Telling, Glenn C., Pandita, Tej K., Hunt, Clayton R., Soto, Claudio
Опубликовано в: J Biol Chem (2019)

Prion disease tempo determined by host-dependent substrate reduction

по Mays, Charles E., Kim, Chae, Haldiman, Tracy, van der Merwe, Jacques, Lau, Agnes, Yang, Jing, Grams, Jennifer, Di Bari, Michele A., Nonno, Romolo, Telling, Glenn C., Kong, Qingzhong, Langeveld, Jan, McKenzie, Debbie, Westaway, David, Safar, Jiri G.
Опубликовано 2014

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrP(Sc) Accumulation

по Westaway, David, Genovesi, Sacha, Daude, Nathalie, Brown, Rebecca, Lau, Agnes, Lee, Inyoul, Mays, Charles E., Coomaraswamy, Janaky, Canine, Brenda, Pitstick, Rose, Herbst, Allen, Yang, Jing, Ko, Kerry W. S., Schmitt-Ulms, Gerold, DeArmond, Stephen J., McKenzie, Debbie, Hood, Leroy, Carlson, George A.
Опубликовано 2011

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

по Lau, Agnes, McDonald, Alex, Daude, Nathalie, Mays, Charles E, Walter, Eric D, Aglietti, Robin, Mercer, Robert CC, Wohlgemuth, Serene, van der Merwe, Jacques, Yang, Jing, Gapeshina, Hristina, Kim, Chae, Grams, Jennifer, Shi, Beipei, Wille, Holger, Balachandran, Aru, Schmitt-Ulms, Gerold, Safar, Jiri G, Millhauser, Glenn L, Westaway, David
Опубликовано в: EMBO Mol Med (2015)

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alle...

по Mercer, Robert C. C., Daude, Nathalie, Dorosh, Lyudmyla, Fu, Ze-Lin, Mays, Charles E., Gapeshina, Hristina, Wohlgemuth, Serene L., Acevedo-Morantes, Claudia Y., Yang, Jing, Cashman, Neil R., Coulthart, Michael B., Pearson, Dawn M., Joseph, Jeffrey T., Wille, Holger, Safar, Jiri G., Jansen, Gerard H., Stepanova, Maria, Sykes, Brian D., Westaway, David
Опубликовано в: PLoS Pathog (2018)