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Modeling amyloid beta and tau pathology in human cerebral organoids

The typical abnormalities observed in the brain of Alzheimer’s disease (AD) patients include synaptic alterations, neuronal death, brain inflammation, and the accumulation of protein aggregates in the form of amyloid plaques and neurofibrillary tangles. Despite the development of many animal and in...

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Foilsithe in:Mol Psychiatry
Main Authors: Gonzalez, Cesar, Armijo, Enrique, Bravo-Alegria, Javiera, Becerra-Calixto, Andrea, Mays, Charles E., Soto, Claudio
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594704/
https://ncbi.nlm.nih.gov/pubmed/30171212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0229-8
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