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Modeling amyloid beta and tau pathology in human cerebral organoids

The typical abnormalities observed in the brain of Alzheimer’s disease (AD) patients include synaptic alterations, neuronal death, brain inflammation, and the accumulation of protein aggregates in the form of amyloid plaques and neurofibrillary tangles. Despite the development of many animal and in...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Gonzalez, Cesar, Armijo, Enrique, Bravo-Alegria, Javiera, Becerra-Calixto, Andrea, Mays, Charles E., Soto, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594704/
https://ncbi.nlm.nih.gov/pubmed/30171212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0229-8
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