Modeling amyloid beta and tau pathology in human cerebral organoids

The typical abnormalities observed in the brain of Alzheimer’s disease (AD) patients include synaptic alterations, neuronal death, brain inflammation, and the accumulation of protein aggregates in the form of amyloid plaques and neurofibrillary tangles. Despite the development of many animal and in...

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Bibliographic Details
Published in:Mol Psychiatry
Main Authors: Gonzalez, Cesar, Armijo, Enrique, Bravo-Alegria, Javiera, Becerra-Calixto, Andrea, Mays, Charles E., Soto, Claudio
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594704/
https://ncbi.nlm.nih.gov/pubmed/30171212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0229-8
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