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Infectious Prions Accumulate to High Levels in Non Proliferative C2C12 Myotubes
Prion diseases are driven by the strain-specific, template-dependent transconformation of the normal cellular prion protein (PrP(C)) into a disease specific isoform PrP(Sc). Cell culture models of prion infection generally use replicating cells resulting in lower levels of prion accumulation compare...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820720/ https://ncbi.nlm.nih.gov/pubmed/24244171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003755 |
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